BACKGROUND Blockade of the renin-angiotensin-aldosterone system in the early post-transplant period remains controversial. Angiotensin II-receptor blockers (ARB) have many benefits to the patient with chronic kidney disease and these benefits may also apply to the renal transplant recipient (RTR). Additionally, there are theoretical benefits of ARB use in RTR. This study was designed to investi...

AIMS The goal was to terminate atrial fibrillation (AF) by targeting atrioventricular differences in ionic properties. METHODS AND RESULTS Optical mapping was used to record electrical activity during carbachol (0.25-0.5 μM)-induced AF in pig hearts. The atrial-specific current, I(Kur), was blocked with 100 μM 4-aminopyridine (4-AP) or with 0.5 μM DPO-1. Hearts in AF and ventricular fibrillat...

A 51-year-old man presented with profuse vomiting and epigastric discomfort. The patient was known to suffer from a bipolar affective disorder with previous hospitalization for psychotic depression and attempted suicide. An ECG tracing showed normal sinus rhythm, inverted T waves in leads II, III and AVF and depressed ST segments in V4–V6 (Figure 1). Laboratory investigations revealed a serum p...

Abstract Background and Aims The aim of our study is to identify the causes non-traumatic rhabdomyolysis in context, clinical biological presentation patients indications renal replacement therapy management this entity. Method Our a monocentric retrospective conducted at universitary hospital Mohamed VI Marrakech including 14 who presented complicated by acute kidney inury (AKI) with no trauma...