Priapism is a prolonged involuntary erection that can have severe complications if left untreated. Ischaemic priapism very rare in children and requires urgent intervention to prevent permanent erectile dysfunction penile shortening. It be caused by ischaemia sickle cell anaemia, leukaemia, trauma, drugs, or idiopathy. Homocystinuria autosomal recessive disorder cause hyperhomocysteinemia hyper...

This article aims to comprehensively describe a particular case of bilateral intraocular subluxated lens with pseudoexfoliation syndrome in Moroccan woman homocystinuria. We report 56-year-old patient who has cataractous along whitish deposits. The association PEX hyperhomocysteinemia rarely been found. It worsens the lenses' zonular stability and causes multiple complications.

High cardiovascular mortality (CVD) determines the relevance of their effective primary and secondary preventive measures, based on principles a clinical-epideomyological approach isolation risk factors (RFs). Until now, CVD have been leading cause deterioration in demographic indicators population all countries. According to WHO, they account for up 31 % deaths 59 deaths. Adherence healthy lif...

Introduction Elevated blood levels of homocysteine have been associated with several psychiatric and neurodegenerative disorders such as schizophrenic disorders, Alzheimer’s disease, Parkinson’s disease depression. The hypothesis is that genetic environmental factors elevate levels, which causes vascular diseases the brain, and/or changes in neurotransmitters, cause various mental disorders. Ob...

Acute mesenteric venous thrombosis (MVT) is an uncommon form of intestinal ischemia with high mortality and usually occurs in the setting of preexisting comorbidities including thrombophilia and abdominal inflammatory conditions. Hyperhomocysteinemia has been known to be a risk factor for thromboembolism, often located on an unusual site. Considering that homocysteine metabolism is determined g...

MTHFR gene variants C677T and A1298C seem to be related to an increased risk of migraine. Folates' metabolism could play a role in the pathophysiology of migraine. We supplemented 16 children with migraine, hyperhomocysteinemia, and MTHFR polymorphisms with folic acid and obtained a resolution/reduction of migraine attacks. Although the mechanism leading to these effects has been not made clear...

Cardiovascular disease is the leading cause of mortality and disability in the western world. In the last years, the accumulation of evidence coming from both retrospective and prospective clinical studies has led to an increased interest in the potential role of mild hyperhomocysteinemia as a major, independent risk factor for cardiovascular disease. The present paper reviews the position of h...