Prochlorperazine is frequently used in the treatment of refractory nausea and migraines. Known side effects include extrapyramidal symptoms such as akathisia and dystonia. We report a pregnant patient taking prochlorperazine for hyperemesis gravidarum who developed hemidystonia, which triggered an acute code stroke response from prehospital, emergency medicine and neurology providers. We suspec...

A 29 year old woman is described with severe hyperemesis gravidarum, atypical migraine, numerous admissions to hospital for psychiatric illness, non-epileptic seizures, and valproate-induced coma. Metabolic studies and measurement of [9,10(n)-3H]palmitate oxidation by cultured fibroblasts suggested a multiple acyl-CoA dehydrogenation disorder. Treatment with riboflavin abolished headaches and a...

OBJECTIVE We evaluated the incidence of hyperemesis between planned and unplanned pregnancy. MATERIALS AND METHODS A prospective study was conducted among 100 women with planned pregnancies and 100 women with unplanned pregnancies. Participants completed a questionnaire to determine the presence of vomiting. If pregnant women had severe vomiting (>3 times per day), urinary investigation was p...

OBJECTIVE To determine whether change in paternity changes recurrence risk of hyperemesis gravidarum (HG). STUDY DESIGN Survey data on recurrence of HG was compared between cases who had a paternity change between pregnancies and cases who did not. RESULTS The percentage of HG pregnancies in women with the same partner for all pregnancies was not significantly different from the percentage ...

It is the object of the writer to approach this question purely from the clinical point of view, and to discuss the best methods at our disposal to combat these most serious diseases. If women in general realized the dangers of the pregnant state and consulted their medical attendants at an earlier period regarding their pregnancy, many cases of Hyperemesis Gravidarum, Acute Yellow Atrophy, Pre...

MacGibbon KW1*, Fejzo, MS2,3 and Mullin PM4 1HER Foundation, Damascus, OR, USA 2Keck School of Medicine, University of Southern California, Department of Maternal-Fetal Medicine, Los Angeles, CA, USA 3University of California, Los Angeles, Department of Medicine, Los Angeles, CA, USA 4Keck School of Medicine, University of Southern California, Department of Maternal-Fetal Medicine, Los Angeles,...

Letter to the editor.