Neonatal Graves' disease presenting as conjugated hyperbilirubinemia is a diagnostic challenge because the differential includes a gamut of liver and systemic diseases. We present a unique case of neonatal Graves' disease in a premature infant with conjugated hyperbilirubinemia born to a mother with hypothyroidism during pregnancy and remote history of Graves' disease. Infant was treated with a...

INTRODUCTION Green pigmentation on the palms and soles in patients with hyperbilirubinemia is a rare entity. Eccrine chromhidrosis is an unusual form of green acral pigmentation characterized by the secretion of colored sweat from the eccrine glands. Rarely, eccrine chromhidrosis can mimic an eczematous process leading to misdiagnosis. We report a case of a patient with hyperbilirubinemia who p...

elevated serum level of bilirubin is a common manifestation which is occurred in several diseases. hyperbilirubinemia can manifest either conjugated or unconjugated. conjugated or direct hyperbilirubinemia usually are caused by hepatocellular diseases or cholestatic liver diseases. merely conjugated hyperbilirubinemia is the main manifestation of two congenital syndromes, including dubin-johnso...

introduction: neonatal hyperbilirubinemia is a common disorder and if untreated is potentially neurotoxic. methods: in order to investigate the correlation between hyperbilirubinemia and hemoglobinopathies, in a prospective study we studied a total 100 full term neonates at nemazi hospital with total bilirubin greater than 15 mg/dl and direct bilirubin less than 1.5mg/dl. other known causes of ...

Background: Perforated appendix can be detected earlier by chemically with the aid of hyperbilirubinemia. It is a simple non-invasive modality that to detecting complicated appendicitis and avoid morbidity. Aim: To assess frequency hyperbilirubinemia in patients undergoing appendectomy due perforated appendicitis. Methods: A descriptive cross-sectional study was conducted which total 75 emergen...

OBJECTIVE Breast milk jaundice is a common problem in nursing infants. It has been ascribed to various breast milk substances, but the component or combination of components that is responsible remains unknown. During our study of defects of the bilirubin uridine diphosphate-glucuronosyltransferase gene (UGT1A1) in patients with hereditary unconjugated hyperbilirubinemia (Crigler-Najjar syndrom...

BACKGROUND Early detection and treatment of neonatal hyperbilirubinemia is important in the prevention of bilirubin-induced encephalopathy. In this study, we evaluated the New Jersey pediatricians' practices and beliefs regarding the management of neonatal hyperbilirubinemia and their compliance with the recommendations made by the American Academy of Pediatrics (AAP) in 1994. METHODS A surve...

Jaundice is a clinical condition that is often present is pediatric practice and constitutes one of the major issues within the neonatal period. Although most newborn with jaundice are otherwise healthy, they need to be monitored because bilirubin is potentially toxic to central nervous system .A prospective cohort study was conducted in Neonatal intensive care unit of Gauhati medical college a...

background: jaundice is one of the most common problems occurring in the neonatal period. it is commonly managed by phototherapy with its inherent complications. however, this treatment modality may itself result in the development of hypocalcaemia and create serious complications including convulsion and related conditions. objective: to determine the effect of phototherapy on serum calcium le...

conclusions according to our study, phototherapy should not be used as prophylactic therapy for all vlbw infants, but rather it should be individualized in order to maintain low bilirubin levels. results the mean bilirubin level on the first day in both groups exhibited no significant difference. the peak serum bilirubin was 7.7 ± 1.4 and 8.5 ± 2.1 mg/dl in the prophylactic and therapeutic grou...