Scalable shared-memory multiprocessors that are designed as Cache-Only Memory Architectures (Coma) allow automatic replication and migration of data in the main memory. This enhances programmability by hopefully eliminating the need for data distribution strategies and page migration schemes. Recently, a variant of Coma called Simple Coma has been proposed as a lower-cost alternative to hardwar...

Scalable shared-memory multiprocessors that are designed as Cache-Only Memory Architectures (Coma) allow automatic replication and migration of data in the main memory. This enhances programmability by hopefully eliminating the need for data distribution strategies and page migration schemes. Recently, a variant of Coma called Simple Coma has been proposed as a lower-cost alternative to hardwar...

Increased brain ammonia concentrations are a hallmark feature of several neurological disorders including congenital urea cycle disorders, Reye's syndrome and hepatic encephalopathy (HE) associated with liver failure. Over the last decade, increasing evidence suggests that hyperammonemia leads to alterations in the glutamatergic neurotransmitter system. Studies utilizing in vivo and in vitro mo...