نتایج جستجو برای: hydroxypropyl γ cyclodextrin
تعداد نتایج: 83373 فیلتر نتایج به سال:
2-Hydroxypropyl-β-cyclodextrin (HP-β-CyD) is a cyclic oligosaccharide that is widely used as an enabling excipient in pharmaceutical formulations, but also as a cholesterol modifier. HP-β-CyD has recently been approved for the treatment of Niemann-Pick Type C disease, a lysosomal lipid storage disorder, and is used in clinical practice. Since cholesterol accumulation and/or dysregulated cholest...
Novel supramolecular hydrogels were formed between pyrene-terminated poly(ethylene glycol) star polymers and γ-cyclodextrin (γ-CD), through the inclusion complexation of dimers of the pyrene terminals with γ-CD, where γ-CD was directly used as a supramolecular cross-linking reagent without any modification.
Development and validation of a simple fast method high-performance liquid chromatography with diode array detection (HPLC-DAD) for the simultaneously analysis rutin, avobenzone, octyl p-methoxycinnamate is presented. These substances were separated using Kromasil C18 (250×4.6 mm, 5 μm) column, methanol: water (88:12 v/v) as mobile phase, flow rate 0.8 mL min−1. The experiment was performed at ...
In this study, an adsorption process using hemp-based materials in felt form was applied to remove between 45 and 53 contaminants present wastewater from the surface treatment industry. Several were compared batch experiments, including a made of 100% hemp fiber (HEMP), same cross-linked with 1,2,3,4-butanetetracarboxylic acid (HEMPBA), coated maltodextrin-1,2,3,4-butanetetracarboxylic polymer ...
The purpose of the present study was to prepare inclusion complex of domperidone with hydroxylpropyl-β-cyclodextrin in order improved the solubility and hence to increase dissolution of domperidone. An effect of concentration of hydroxylpropyl-β-cyclodextrin on the aqueous solubility of domperidone was determined by phase-solubility method. The aqueous solubility of domperidone increased as a f...
Introduction Toltrazuril (Tol) is used to prevent and combat coccidiosis. However, its low aqueous solubility and poor oral bioavailability limit clinical application. Methods To overcome the shortcomings, toltrazuril-hydroxypropyl-β-cyclodextrin inclusion complex (Tol-HP-β-CD) was prepared and characterized. The comparative plasma disposition kinetics of Tol was analyzed after a single orall...
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