A simple and efficient one-pot, three-component Strecker reaction of protected amino acids, aromatic aldehydes, and trimethylsilyl cyanide has been developed for the synthesis of chiral α-amino nitriles. The reaction was carried out in the presence of catalytic amount of phosphotungstic acid (H3[P(W3O10)4]) as an environmentally friendly cata...

enzymatic hydrolysis of yellowfin tuna visceral protein with neutrase has been carried out by response surface methodology using factorial design. peptide chain length was estimated as the response surface to the hydrolysis conditions (enzyme activity, reaction temperature, and reaction time). the tuna visceral protein hydrolysate had relatively high protein (74.56%) and low lipid content (1.86...

The title compound C11H10BrN, has an E conformation at the C=C bond of the acrylo-nitrile unit. The vinyl group makes a dihedral angle of 44.53 (12)° with the benzene ring. In the crystal, weak C-H⋯π inter-actions involving the benzene ring are observed.

The hydration numbers of typical aprotic polar substances bearing dipole moments larger than 3 D, such as nitro compounds and nitriles, were precisely determined in aqueous solution using high frequency dielectric relaxation techniques up to a frequency of 50 GHz at 25 °C. The hydration number is one of the most quantitative parameters for determining the hydrophilicity or hydrophobicity of a c...

this research proposes an efficient and easy procedure for the preparation of amides or nitriles from aldehydes. such materials were prepared via one-pot three component condensation reaction of various aldehydes in the presence of nano-ticl4.sio2 as a catalyst under thermal conditions. all reactions proceeded in high yields and in a moderately short reaction time. meanwhile, oximes were obtain...

Next-generation DNA sequencing (NGS) has made it feasible to sequence large number of microbial genomes and advancements in computational biology have opened enormous opportunities to mine genome sequence data for novel genes and enzymes or their sources. In the present communication in silico mining of microbial genomes has been carried out to find novel sources of nitrilases. The sequences se...

Protein recovery under sonication treatment and autolysis, also protein hydrolysis progress during enzymatic hydrolysis (using trypsin and chymotrypsin) and autolysis (using endogenous enzymes) were investigated in Saccharomyces cerevisiae and Kluyveromyces marxianus. Crude protein content of dried yeast cells were 53.22% and 45.6% for S.cerevisiae and K.marxianus, respectively. After 96 hrs of...

Nitriles play a key role as molecular precursors in prebiotic experiments based on the RNA-world scenario for origin of life. These chemical compounds could have been partially delivered to young Earth from extraterrestrial objects, stressing importance establishing reservoir nitriles interstellar medium. We report here detection towards cloud G+0.693?0.027 several nitriles, including cyanic ac...

pectin is used as gelatinizing agent in food industry. in this study pectin was extracted from five commercial sugar beet varieties namely: doroty, rasul, 7112, br1 and ic using pre-hydrolysis technique. experiments were conducted using factorial design to verify the effect of temperature, time, percentage of hcl and water requirements on the extraction rate of pectin. the qualitative factors o...