Both MAT-B1 (nontransplantable) and MAT-Cl (xenotransplantable) ascites sublines of the 13762 rat mammary adenocarcinoma contain a major sialoglycoprotein (ASGP-1) with low electrophoretic mobility in dodecyl sulfate. ASGP-1 from each subline is rapidly purified by density gradient centrifugation of membrane fragments in cesium chloride containing 4 M guanidine hydrochloride. The products give ...

Buprenorphine is a partial mu agonist and kappa antagonist which is used for the treatment of pain and opioid addiction. A mixture of buprenorphine hydrochloride and naloxone hydrochloride has been approved for the treatment of opioid dependence.In this study a third order derivative spectrophotometric method based on zero-crossing technique has been used for the simultaneous determination of b...

A fast and sensitive UHPLC-DAD method was developed and subsequently validated for determination of cefetamet pivoxil hydrochloride in the presence of its degradation products. The chromatographic separation was carried out on a Waters Acquity BEH C18, (2.1 x 100 mm, 1.7 µm) column. The mobile phase was composed of 0.1% formic acid and acetonitrile (40 : 60, v/v) at the flow rate 0.7 mL/min. Th...

Abstract: Aim: The present study aims at exploring the development of xylometazoline hydrochloride loaded chitosan nanoparticles (XYL-NP) cross linked with calcium chloride for treatment nasal congestion. Materials and Methods: XYL-NP were prepared using different polymer like chitosan, linking agent glacial acetic acid as a solvent enhancer ionotropic gelation method, which was further optimiz...

The coordination behavior of three ligand precursors 2-[(2- pyridinylmethyl)amino]acetic acid hydrochloride, 4-[(2- pyridinylmethyl)amino]benzoic hydrochloride and 4-{[2-(pyridin-2- ylmethylamino)ethylamino]methyl}benzoic HL1?HCl- HL3?HCl, respectively, in copper(II) complexes is described. were characterized by elemental analysis, ESI mass spectrometry IR spectroscopy, as well X-ray structural...

combination dosage forms of naproxen sodium and pseudoephedrine hydrochloride are used for symptomatic treatment of cold and sinus disorders. in this study, fourth-order derivative spectrophotometric method was used for simultaneous determination of naproxen sodium and pseudoephedrine hydrochloride. the method was linear over the range of 2-28 μg/ml for pseudoephedrine hydrochloride and 4-200 μ...

two simple, accurate and precise methods for simultaneous estimation of esomeprazole and itopride in bulk drug and tablet dosage form have been described. method-a employs formation and solving of simultaneous equation using 231 and 370 nm as two analytical wavelengths. method -b is absorption ratio method, which uses 308 and 331 nm as two analytical wavelengths.beer’s law was obeyed in the con...

The subunit interactions of fumarase have been examined as a function of enzyme concentration, pH, and concentration of guanidine hydrochloride. Fumarase was found to dissociate, with loss of activity, either at low concentrations of the enzyme ( 1 M). At pH 9 a species of enzyme was produced which was ...