Background: According to the World Health Organization (WHO), human resources is the key ingredient to the effective functioning of health systems. The growing human resource crisis in low-income countries has re-energized the debate concerning the role of community health volunteers in health service delivery. Researchers have studied task-shifting among community volunteers focusing on its im...

BACKGROUND Immunizing human volunteers by mosquito bite with radiation-attenuated Plasmodium falciparum sporozoites (RAS) results in high-level protection against infection. Only two volunteers have been similarly immunized with P. vivax (Pv) RAS, and both were protected. A phase 2 controlled clinical trial was conducted to assess the safety and protective efficacy of PvRAS immunization. METH...

Cervical cancer is a global health concern. Persistent oncogenic human papillomavirus (HPV) infection prerequisite for the development of cervical cancer. Emerging research indicates that vaginal microbiota may play both protective and harmful roles in acquisition persistence HPV This multicenter cohort study mainly aims to reveal association with outcome six months women reproductive age. We w...

objective: to evaluate the knowledge, attitude, and preparedness of mahabad red crescent society volunteers in dealing with chemical attacks. methods: this prospective cross-sectional study was conducted on 120 red crescent society volunteers in mahabad city, iran, during 2014-2015.the knowledge of the volunteers was evaluated and rated using a questionnaire as poor, moderate, and good. also, t...

Candidate vector vaccine strain CVD 906 (aroC- and aroD- derivative of virulent Salmonella typhi strain ISP1820) was evaluated in phase 1 clinical trials. The first nine volunteers ingested a single dose of 5 x 10(7) CVD 906 bacilli. At this dose CVD 906 stimulates remarkable systemic and mucosal immune responses, inasmuch as 89% of volunteers developed marked serum antibody levels to S. typhi ...

In vitro and in vivo skin absorption of the pesticide propoxur (2-isopropoxyphenyl N-methyl carbamate, commercially Baygon(TM) and Unden (TM); log Po/w 1.56, MW 209.2) was investigated. In vivo studies were performed in rats and human volunteers, applying the test compound to the dorsal skin and the volar aspect of the forearm, respectively. In vitro experiments were carried out in static diffu...

the main aim of this study was to find a suitable rabies vaccination protocol which would allow usage of lower volumes of vaccine, fewer clinical visits and above all, enough serological effectiveness for high-risk individuals requiring pre-exposure immunization. human diploid cell rabies vaccine was administered intradermally and intramuscularly in 60 previously unvaccinated volunteers, aged 1...

There is evidence that MRSA ST398 of animal origin is only capable of temporarily occupying the human nose, and it is therefore, often considered a poor human colonizer.We inoculated 16 healthy human volunteers with a mixture of the human MSSA strain 1036 (ST931, CC8) and the bovine MSSA strain 5062 (ST398, CC398), 7 weeks after a treatment with mupirocin and chlorhexidine-containing soap. Bact...

C5a is an 11,000-D fragment of the fifth component of complement (C5) with potent anaphylatoxic and leukocyte chemotactic activities. C5a is believed to play an important role in the pathophysiology of certain skin disorders and systemic diseases with cutaneous manifestations. However, there is very little known about the in vivo reactivity of C5a in man. In this study we examined the effects o...