نتایج جستجو برای: human chromosomes

تعداد نتایج: 1689246  

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2005
Yesu Jeon Stefan Bekiranov Neerja Karnani Philipp Kapranov Srinka Ghosh David MacAlpine Charles Lee Deog Su Hwang Thomas R Gingeras Anindya Dutta

Chromosomes in human cancer cells are expected to initiate replication from predictably localized origins, firing reproducibly at discrete times in S phase. Replication products obtained from HeLa cells at different stages of S phase were hybridized to cDNA and genome tiling oligonucleotide microarrays to determine the temporal profile of replication of human chromosomes on a genome-wide scale....

Journal: :Cytogenetic and genome research 2015
Narjes Armanet Lucie Tosca Sophie Brisset Thomas Liehr Gérard Tachdjian

Small supernumerary marker chromosomes (sSMC) are structurally abnormal chromosomes that cannot be unambiguously identified by banding cytogenetics. The objective of this study was to provide an overview of sSMC frequency and characterization in a context of infertility and to review the literature describing sSMC in relation with male and female infertility. Therefore, a systematic literature ...

Journal: :The Journal of Cell Biology 1964
Maimon M. Cohen Margery W. Shaw

Mitomycin C (MC) is a chemically reactive antibiotic derived from Streptomyces caespitosus. The drug selectively inhibits DNA synthesis (2, 15, 29, 34, 39, 40, 43, 44, 49) and degrades cellular DNA but does not affect the synthesis of R N A or protein (31, 33, 40). MC induces bacteriophage production in lysogenic bacteria (23, 29), increases the rate of genetic recombination among mutant forms ...

Journal: :Journal of Histochemistry & Cytochemistry 1989

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