The unsatisfactory standardization of many immunoassays is fairly well recognized, but the problem is hard to tackle (1 ). Recently, studies on the performance of immunoassays for testosterone in female serum (2 ) and for urinary cortisol (1 ) have revealed that the quality of some widely used assays is totally unsatisfactory. The quality of assays for human chorionic gonadotropin (hCG) has als...

nonsignificant differences between cutoffs for serum and plasma and between assays are encouraging regarding the ease of interpretation by clinicians and laboratories. Also encouraging were improvements in the analytical sensitivity of these newergeneration assays. Interestingly, only 3 samples were identified as above the 99th percentile by all 3 assays. The mechanisms responsible for this lac...

background: the most frequent physical finding in infertile men is varicocele, in which one of the mechanisms that can affect seminal parameters is oxidative stress. objective: our study aimed, for the first time, to compare the efficacy of recombinant human follicle-stimulating hormone (rhfsh), human chorionic gonadotropin (hcg) and human menopausal gonadotropin (hmg) on sperm parameters and f...

Background: Human chorionic gonadotropin (hCG) is a member of glycoprotein hormones family consist of two different non-covalently heterodimeric chains: alpha and beta subunits with 92 and 145 amino acids respectively. This hormone plays an important role in human reproduction and physiology especially for maintenance of the corpus luteum during the first months of pregnancy Materials and Metho...

Early growth response factor (Egr-1) is an inducible zinc finger transcription factor that binds specific GC-rich enhancer elements and impacts female reproduction. These studies document for the first time that FSH rapidly induces Egr-1 expression in granulosa cells of small growing follicles. This response is transient but is reinitiated in preovulatory follicles exposed to the LH analog, hum...

introduction: considering the high incidence of preterm labor and its known complications, and that human myometrium contains receptors for human chronic gonadotropin (hcg) and that hcg can inhibit myometrial contractions on vitro, made me study treating effects of hcg on preterm labor. this clinical trial study was carried out to compare the effect of hcg, and magnesium sulfate (mgso4) on prev...

1. Kovalevskaya G, Birken S, Kakuma T, Ozaki N, Sauer M, Lindheim S, et al. Differential expression of human chorionic gonadotropin (hCG) glycosylation isoforms in failing and continuing pregnancies: preliminary characterization of the hyperglycosylated hCG epitope. J Endocrinol 2002;172:497–506. 2. Elliott MM, Kardana A, Lustbader JW, Cole LA. Carbohydrate and peptide structure of the and -sub...