Calcium and phosphorus metabolism involves in patients with chronic kidney disease-mineral bone disorder (CKD-MBD). Sclerostin morphogenetic protein-7 (BMP-7) are closely related to formation. This study aims assess sclerostin BMP-7’s role renal function, blood calcium CKD-MBD. 86 CKD-MBD were collected as the case group healthy subjects selected control group. ELISA was used detect BMP-7 serum...

Bone morphogenetic proteins (BMPs) are a group of growth factors also known as cytokines and as metabologens. Originally discovered by their ability to induce the formation of bone and cartilage, BMPs are now considered to constitute a group of pivotal morphogenetic signals, orchestrating tissue architecture throughout the body. The important functioning of BMP signals in physiology is emphasiz...

OBJECTIVES The purpose of this article was to review and critically assess the use of platelet rich plasma, recombinant human bone morphogenetic protein-2 and different scaffolds (i.e. tricalciumphosphate, polycaprolactone, demineralized bone matrix and anorganic bovine bone mineral) in oral and maxillofacial surgery comparing the relevant literature and own clinical experience. MATERIAL AND ...

Chronic renal failure is complicated by high cardiovascular mortality. One key contributor to this mortality is vascular calcification, for which no therapy currently exists. Bone morphogenetic protein 7 is an essential renal morphogen that maintains renal tubular differentiation in the adult and is downregulated in renal failure. Several studies have demonstrated its efficacy in treating vario...