نتایج جستجو برای: human adenocarcinoma gastric cell line ags

تعداد نتایج: 3287635  

Journal: :Oncology reports 2008
Jeong-Hyung Lee

Two human gastric cancer cell lines of differing invasive potential, SNU-484 and SNU-638 cells, were examined using subtractive suppression hybridization in a search for any genes associated with metastasis. Of the eight cDNAs identified as being differentially expressed genes, it was determined that humbug, which encodes a truncated isoform of aspartyl (asparaginyl) beta-hydroxylase (AAH) miss...

Journal: :the iranian journal of pharmaceutical research 0
shaya mokhtari department of medicinal chemistry, school of pharmacy, shahid beheshti university of medical sciences, tehran, iran. student research committee, school of pharmacy, shahid beheshti university of medical sciences, tehran, iran. mahmoud mosaddegh traditional medicine and materia medica research center, shahid beheshti university of medical sciences, tehran, iran. maryam hamzeloo moghadam traditional medicine and materia medica research center, shahid beheshti university of medical sciences, tehran, iran. zohreh soleymani department of medicinal chemistry, school of pharmacy, shahid beheshti university of medical sciences, tehran, iran. saeideh ghafari traditional medicine and materia medica research center, shahid beheshti university of medical sciences, tehran, iran farzad kobarfard department of medicinal chemistry, school of pharmacy, shahid beheshti university of medical sciences, tehran, iran. pharmaceutical research sciences center, shahid beheshti university of medical sciences, tehran, iran. phytochemistry research center, shahid beheshti university of medical sciences, tehran, iran.

the assessment of the degree or rate of cellular proliferation and cell viability is critical for the assessment of the effects of drugs on both normal and malignant cell populations. in the present study, a few novel 3-substituted derivatives of 2-indolinones were synthesized by condensation of substituted oxindole or isatin derivatives with appropriate aldehydes or primary aromatic amines res...

Journal: :Chronic Diseases and Translational Medicine 2023

Background It is of great clinical significance to further explore new strategies and potential combined therapeutic targets for gastric cancer. This study aimed investigate the synthetic lethal effect RBBP8 molecular intervention with a poly ADP ribose polymerase (PARP) inhibitor in non-BRCA mutant cancer clarify mechanism by which regulates homologous recombination repair. Methods The role DN...

Journal: :Infection and immunity 2004
Victoria S Conlin Susan B Curtis Ying Zhao Edwin D W Moore Valerie C Smith R Mark Meloche B Brett Finlay Alison M J Buchan

The human gastric pathogen Helicobacter pylori attaches to antral epithelial cells in vivo. Cultured human antral epithelial cells, AGS and NCI-N87 cell lines, were grown in the absence or presence of H. pylori and compared with respect to gene transcript levels, protein expression, organization of the actin cytoskeleton, and the regulation of cell migration. The Clontech Neurobiology array det...

Journal: :The Biochemical journal 2011
Fan Lian Xiangbin Xing Gang Yuan Claus Schäfer Sandra Rauser Axel Walch Christoph Röcken Martin Ebeling Matthew B Wright Roland M Schmid Matthias P A Ebert Elke Burgermeister

Bile acids from duodenogastric reflux promote inflammation and increase the risk for gastro-oesophageal cancers. FXR (farnesoid X receptor/NR1H4) is a transcription factor regulated by bile acids such as CDCA (chenodeoxycholic acid). FXR protects the liver and the intestinal tract against bile acid overload; however, a functional role for FXR in the stomach has not been described. We detected F...

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