BLAIR-WEST, J. R., J. I? COGHLAN, D. A. DENTON, J. W. FUNDER, B. A. SCOGGINS, AND R. D. WRIGHT. Inhibition of renin secretion by systemic and intrarenal angiotensin infusion. Am. J. Physiol. 220(5): 1309-1315. 197 1 .-Conscious sheep were allowed to become sodium depleted by loss of parotid saliva for 24 or 48 hr. Angiotensin II was infused continuously intravenously at 10, 20, or 60 pg/hr or i...

Objective: Angiotensin II (Ang II), the main product of renin-angiotensin system (RAS) has a well-known role in cardiovascular regulation. Over-production of Ang II is one of the important underlying mechanisms of hypertension. In this study, the effect of crocin on cardiovascular responses in rats with acute hypertension induced by Ang II was evaluated. Materials and methods: Rats were divided...

OBJECTIVE To test the validity of ambulatory heart rate (HR) assessment with a cuff ambulatory blood pressure (ABP) monitor. DESIGN Cross-instrument comparison of HR measured intermittently by a cuff ABP monitor (SpaceLabs, Redmond, Washington, USA), with HR derived from continuous electrocardiogram (ECG) recordings (1) in a controlled laboratory experiment and (2) during long-term recording ...

Background and Aim: The Gow-Gates (GG) block and the inferior alveolar nerve block (IANB) can be used interchangeably for anesthetizing mandibular molars. The aim of this study was to compare these two injections in root canal therapy of mandibular molars with regard to heart rate (HR) and blood oxygen saturation (BOS) changes. Materials and Methods: Thirty patients between the ages of 18-70 y...

Background Numerous articles reported that dysregulated expression levels of miRNAs correlated with survival time of HCC patients. However, there has not been a comprehensive meta-analysis to evaluate the accurate prognostic value of miRNAs in HCC. Design Meta-analysis. Materials and Methods Studies, published in English, estimating expression levels of miRNAs with any survival curves in HC...

The rhino mouse, a single gene recessive mutation, is characterized by abnormal epidermal differentiation and maturation leading to the loss of hair at 1 month of age as well as follicular and epidermal hyperkeratoses. We evaluated the lids and corneas of nine rhino mice and their normal litter mates at various ages from 3 months to 1 year. Tissue specimens were studied by light microscopy, sca...

We investigated the effects of the immunosuppressant HR-325 on arterial lesions in Dahl rats with saltinduced hypertension. Forty-eight 6-wk-old Dahl salt-sensitive (DS) rats were divided into 1) a low-salt (0.3% NaCI) group, 2) a high-salt (4% NaCI) group, 3) a high-salt and low-dose (1 mg/kg) HR-325 group, and 4) a high-salt and high-dose (30 mg/kg) HR-325 group. The rats were treated for 8 w...

background intravenous opioids are administered to prevent and control hemodynamic changes due to endotracheal intubation. except for special cases such as preeclampsia, these drugs are not recommended for parturants candidate for cesarean section because of the respiratory depression caused in the newborn. objectives according to rapid metabolism of remifentanil, the current study aimed to com...