We compared whole-exome sequencing (WES) and whole-genome sequencing (WGS) in six unrelated individuals. In the regions targeted by WES capture (81.5% of the consensus coding genome), the mean numbers of single-nucleotide variants (SNVs) and small insertions/deletions (indels) detected per sample were 84,192 and 13,325, respectively, for WES, and 84,968 and 12,702, respectively, for WGS. For bo...

The formation and entrapment of tris(8-hydroxyquinoline)aluminum (Alq₃) molecules on the surface of anodic porous alumina (APA) immersed in an ethanol solution of 8-hydroxyquinoline (HQ) were investigated by absorption, fluorescence, and Raman spectroscopies. The effects of the selected APA preparation conditions (galvanostatic or potentiostatic anodization method, anodizing current and voltage...

OBJECTIVES The purpose of this study was to identify apoptosis-inducing factor (AIF) as a cardiac mitochondrial antioxidant and assess the efficacy of EUK-8, a salen-manganese catalytic free radical scavenger, to protect the AIF-deficient myocardium against pressure overload. BACKGROUND Oxidative stress has been postulated to provoke cell death and pathologic remodeling in heart failure. We r...

For a risk variable X and a normalized Young function φ(·), the Haezendonck– Goovaerts risk measure for X at level q ∈ (0, 1) is defined as Hq[X] = infx∈R (x + h), where h solves the equation E [φ ((X − x)+/h)] = 1 − q if Pr(X > x) > 0 or is 0 otherwise. In a recent work, we implemented an asymptotic analysis for Hq[X] with a power Young function for the Fréchet, Weibull and Gumbel cases separa...

A difference operator realization of quantum deformed oscillator algebra Hq(1) with a Casimir operator freedom is introduced. We show that thisHq(1) have a nonlinear mapping to the deformed quantum su(2) which was introduced by Fujikawa et al. We also examine the cyclic representation obtained by this difference operator realization and the possibility to analyze a Bloch electron problem by Hq(...

Acute myeloid leukaemia (AML) is associated with exposure to benzene and treatment with chemotherapeutic agents. It is thought to arise from damage to specific regions of DNA, resulting in chromosome rearrangements or loss. For instance, a deletion on the long arm of chromosome 5 [e.g. del(5q31)] is common in AML patients previously treated with alkylating agents, such as melphalan, or exposed ...

The management of human resources in headquarters (HQ)‐subsidiary relationships requires intensive communication, but effective communication often depends on having a shared language. Hence, language differences can be a serious threat to the successful management of human resources in multinational corporations (MNCs). In this large‐scale quantitative study, encomp...

Previous studies have shown that long noncoding RNAs (lncRNAs) were related to human carcinogenesis and might be designated as diagnosis and prognosis biomarkers. Hydroquinone (HQ), as one of the metabolites of benzene, was closely relevant to occupational benzene poisoning and occupational leukemia. Using high-throughput sequencing technology, we investigated differences in lncRNA and mRNA exp...

We apply an organizational embeddedness perspective to examine international assignees’ retention with the organization. Specifically, we hypothesize that assignees’ social ties within and their perceived fit with the host unit positively relate to two sacrifices with leaving the organization: their firmspecific learning during the assignment and their perceived career prospects in the organiza...