The receptor for advanced glycation endproducts (RAGE) interacts with distinct ligand families linked to the inflammatory response. Studies in animal models suggest that RAGE is upregulated in the inflamed joint and that blockade of the receptor, using a ligand decoy soluble form of RAGE (sRAGE), attenuates joint inflammation and expression of inflammatory and tissue-destructive mediators. In t...

A new analysis method is introduced for investigating whether major flares are clustered in certain fixed regions of the Sun in rigidly-rotating coordinate systems. This method is applied to analysis of major flares of solar cycles 19–23. Northern and southern hemispheres are separately analyzed, and it is found that longitude distributions of flares in the two hemispheres are different. Theref...

conclusions the mean heart rate was higher in participants who were overweight than those with normal weight. results the mean and standard deviation of the heart rate in the hot climatic condition and moderate exercise were 103.84 (3.34) for normal weight subjects and 108.67 (3.27) for overweight subjects. the mean and standard deviation of the heart rate in a very hot climatic condition and l...

Background: In Iran, architectures are often unaware of the risk of radon inhalation and how to reduce radon levels. Furthermore, radon considerations are not implemented in construction methods, construction materials and building utilization by regulatory authorities. Materials and Methods: In this study after reviewing the meteorological changes of Ramsar over the past 50 years (1955-2005), ...

Introduction: Radon-222 gas is a radioactive, colorless and odorless element that can cause lung cancer and stomach in humans with alpha-ray emissions. An important source of Radon-222 is the output water in springs, especially hot springs to emit ionision radiation. In this study, Rn-222 activity concentration and gamma dose rate levels in water sample of some selected hot spr...

Recently, the conversion of HOV lanes to HOT lanes has been increasingly popular in the United States. Several empirical studies have explored the benefits and costs associated with the conversion. However, few quantitative studies have been performed to examine the impact of HOV-to-HOT conversion on traffic safety. Introduction With the hope of relieving highway congestion and generating reven...

INTRODUCTION Many countries still have unacceptably high hospitalizations and deaths from scalds from hot tap water. Prevention strategies implemented in some countries may not work in others. Legislation aimed at changing environments that are conducive to hot tap water scalds may not be effective in many situations for a number of reasons, including lack of acceptability and practicality. M...

In the last decade, the U.S. Food and Drug Administration (FDA) has issued several warnings and recalls for food products that exceed FDA standards for lead. Products containing chili peppers and salt were often suspected as sources of lead contamination, and included items such as candy that are routinely investigated. However, products such as hot sauces that contain similar ingredients have ...