objectives: aim of the present work was to investigate the anti-inflammatory, analgesic and antiulcer effects of red seaweed porphyra vietnamensis (p. vietnamenis). materials and methods: aqueous (por) and alcoholic (pe) fractions were successfully isolated from p. vietnamenis. further biological investigations were performed using a classic test of paw edema induced by carrageenan, writhing in...

background and aims: inflammation is one of the defense mechanisms of body and unpleasant sensation of pain is caused by tissue damage. mostly, inflammation occurs through the release of inflammatory mediators. salvia officinalis is one of the most valuable medicinal kind of mint order. salvigenin is one of the active flavonoids existing in this plant. the aim of this study was to evaluate the ...

The aqueous leaves extract of Ocimum gratissimum was investigated for anti-nociceptive and anti-inflammatory effects in mice and rats. The models used to study the effect on nociception are the acetic acid-induced abdominal constriction test, hot-plate method in mice. The anti-inflammatory effect was investigated employing the formalin-induced hind-paw oedema in rats. The extract caused a signi...

AIM To compare stress resistance increasing and analgesic activities of piperlongumine and a methanolic Piper longum fruit extract (PLE). METHODS Efficacies of a single and repeated daily oral doses (1-256 mg/kg/day) of PLE, piperlongumine, and 50 mg/kg/day doxycycline against foot shock stress triggered alteration in body weights and core temperatures, and of their 11 daily doses on antidepr...

Aim: To evaluate the analgesic activity of aqueous extract of S. hispida on thermal and chemical method induced pain in mice. Materials and methods: 48 Adult albino mice (Swiss strain) weighing 25-30 gm were selected. 24 animals were allocated to each experimental model, in each model there were 4 groups. The control group received vehicle (10 ml /kg, p.o), standard group aspirin (300 mg /kg, p...

AIM The aim was to evaluate the analgesic, anti-inflammatory, and anti-hyperlipidemic activities of Commiphora molmol extract (CME) and its effects on body weight and blood lipids. MATERIALS AND METHODS The analgesic effect was assessed using thermal (hot plate test) and chemical (writhing test) stimuli to induce central and peripheral pain in mice. The anti-inflammatory activity was determin...

BACKGROUND Persicaria hydropiper (Linn.) Delarbre is a common plant of Polygonaceae family commonly called Bishkatali in Bangladesh. Leaves of the plant are traditionally used in the treatment of rheumatic pain, gout, and skin diseases such as ringworms, scabies, boils, abscesses, carbuncles, bites of snakes, dogs or insects. This study evaluated the antinociceptive effect of the methanol extra...

The periaqueductal grey (PAG) area is involved in pain modulation as well as in opiate-induced anti-nociceptive effects. The PAG possess dopamine neurons, and it is likely that this dopaminergic network participates in anti-nociception. The objective was to further study the morphology of the PAG dopaminergic network, along with its role in nociception and opiate-induced analgesia in rats, foll...

The purpose of the hot rolling mill is to make a preheated steel block thinner and longer, see Figure 1. This is done by pulling the plate through two parallel rolls mounted in the rolling mill. Due to the large forces obtained in hot rolling, the elastic de ection of the rolling mill is of the same order of magnitude as the plate thickness. Variations in the rolling force caused by variations ...

Leonurus cardiaca, commonly known as motherwort, is a member of the Lamiaceae family. It has a number of interesting biological activities, for example, sedative and hypotensive, antioxidant, anti-inflammatory, and antimicrobial activities. The aim of the present study was to investigate the effect of alcoholic extract of aerial part of Leonurus cardiaca on nociceptive response using formalin, ...