A healthy 27-year-old female presented to the hospital after she collapsed an hour into her first marathon run on a hot humid day. On presentation, she was hyperthermic, encephalopathic, tachycardic, and hypotensive. On admission, she was found to have lactic acidosis, rhabdomyolysis, and acute kidney injury and was treated with cold normal saline and cooling blankets. She subsequently started ...

It’s a boy! Or is it? We live in an era of blurred gender lines, but for many reptiles this has always been a hot topic. In crocodilian as well as several turtle species, cranking up the thermostat a few degrees during a critical developmental window, called the thermo-sensitive period, will turn a whole clutch of eggs into males. Hormones also contribute to sex determination in these species, ...

The craze for miniaturization has swept o’er most every nation, but should a hand e’er so slightly tremble no micro-machine can it assemble: and so all those really small bits leave the technicians in fits and the hope for a lab on a chip might seem frightfully flip. Yet, while optical forces are weak they provide the control that we seek. When light’s holographically defined, HOT opportunities...

Educational Modelling Languages (EMLs) have been proposed to enable the authoring of models of learning units (e.g., courses, lessons, lab practices, seminars) covering the broad variety of pedagogical approaches. In addition, some EMLs have been proposed as computational languages that support the processing of learning unit models by appropriate Learning Management Systems (LMSs). In this con...

We have developed a ten-week curriculum for molecular biology that uses 16S ribosomal RNA genes to characterize and compare novel bacteria from hot spring communities in Yellowstone National Park. The 16S rRNA approach bypasses selective culture-based methods. Our molecular biology course offered the opportunity for students to learn broadly applicable methods while contributing to a long-term ...