Background Febrile neutropenia with childhood cancer alters the outcome significantly. To study the clinical and laboratory parameters, which predict the outcome among cancer patients with febrile neutropenia this study was undertaken. Materials and Methods The study included children less than 18 years with febrile neutropenia episodes. Clinical and hematological / laboratory parameters were r...

BACKGROUND Therapeutic hypothermia is recommended for the treatment of neurological injury after resuscitation from out-of-hospital cardiac arrest. Laboratory studies have suggested that earlier cooling may be associated with improved neurological outcomes. We hypothesized that induction of therapeutic hypothermia by paramedics before hospital arrival would improve outcome. METHODS AND RESULT...

BACKGROUND Timely recognition and prevention of health problems among elderly people have been shown to improve their health. In this randomized controlled trial the authors examined the impact of preventive home visits by a nurse compared with usual care on the outcomes of frail elderly people living in the community. METHODS A screening questionnaire identified eligible participants (those ...

BACKGROUND Lumbar disc herniation and stenosis that results in compression of a nerve root lateral to the foramen is defined as extraforaminal. In recent years the recognition of such pathology has increased with technology and greater awareness. Various approaches and techniques have been developed for extraforaminal decompression in the lumbar region. The purpose of this study was two fold: 1...

Objectives We aim to explore differences in mortality between patients admitted during working hours (8am-5pm on weekdays and 8am-11am on weekends) compared to those admitted after hours. Methods This is a retrospective cohort study of admissions to a medical ICU in a tertiary teaching hospital between 2010-2014. All patients with known APACHE II scores were analysed. Primary outcome measure wa...

BACKGROUND Mortality may be higher for admissions at odd hours than during daytime, although for trauma patients results are conflicting. The objective of this study was to assess whether diurnal differences in mortality among severely injured trauma patients in Denmark were present. METHODS This observational cohort study was conducted between 1 December 2009 and 30 April 2011 involving one ...

BACKGROUND An intervention movement in managed care, disease management (DM), is a system of coordinated health care interventions and communication for populations with conditions in which patient self-care efforts are significant. Another managed care intervention movement, pay for performance (P4P), involves an incentive component in which payment is defined based on meeting specific, previo...

conclusions the survival rate after in-hospital cpr was very low. the duration of cpr and the time of initiating cpr effects patients’ outcomes. these findings highlight the crucial role of an organized, skilled, well-established and timely cpr team. background despite several studies, there is no agreement on factors that affect survival after in-hospital cardiopulmonary resuscitation (cpr). o...

Objective: Our objective was to know the percent mortality of ventricular arrhythmia (VA) storm, its major leading factor and predictors in-hospital VA storm in our population. Methodology: In this retrospective observational study conducted at The Aga Khan University Hospital Karachi, all patients with age ≥16, were included. Baseline demographic, clinical characteristics, laboratory parameter...