Neurons in the mammalian central nervous system are generated from progenitor cells near the lumen of the neural tube. Time-lapse microscopy of dividing cells in slices of developing cerebral cortex reveals that cleavage orientation predicts the fates of daughter cells. Vertical cleavages produce behaviorally and morphologically identical daughters that resemble precursor cells; these symmetric...

Attempts to profile authors according to their characteristics extracted from textual data, including native language, have drawn attention in recent years, via various machine learning approaches utilising mostly lexical features. Drawing on the idea of contrastive analysis, which postulates that syntactic errors in a text are to some extent influenced by the native language of an author, this...

During its development years, geophysical survey has served field archaeology by defining possible sites underground, prior to excavation or preservation. Now we can see the art taking off as a research method in its own right. After summarising some recent research applications of magnetic mapping, the author gives us three case studies from USA and Jordan, where groundpenetrating radar (GPR) ...

High computational requirements combined with rapidly evolving video coding algorithms and standards are a great challenge for contemporary encoder implementations. Rapid specification changes prefer full programmability and configurability both for software and hardware. This paper presents a novel scalable MPEG-4 video encoder on an FPGA-based multiprocessor systemon-chip (MPSOC). The MPSOC a...

Traditionally the vertical slice and the whole-mount preparation of the retina have been used to study the function of retinal circuits. However, many of retinal neurons, such as amacrine cells, expand their dendrites horizontally, so that the morphology of the cells is supposed to be severely damaged in the vertical slices. In the whole-mount preparation, especially for patch-clamp recordings,...

Oligomeric amyloid-beta (Abeta) interferes with long-term potentiation (LTP) and cognitive processes, suggesting that Abeta peptides may play a role in the neuronal dysfunction which characterizes the early stages of Alzheimer's disease (AD). Multiple lines of evidence have highlighted RAGE (receptor for advanced glycation end-products) as a receptor involved in Abeta-induced neuronal and synap...

21 Neocortical neurons in vivo receive concurrent synaptic inputs from multiple sources, 22 including feedforward, horizontal, and feedback pathways. Layer 2/3 of the visual cortex 23 receives feedforward input from layer 4 and horizontal input from layer 2/3. Firing of the 24 pyramidal neurons, which carries the output to higher cortical areas, depends critically 25 on the interaction of these...

Correlated neuronal activity is ubiquitous in developing nervous systems, where it may introduce spatiotemporal coherence and contribute to the organization of functional circuits. In this report, we used voltage-sensitive dyes and optical imaging to examine the spatiotemporal pattern of a spontaneous network activity, giant depolarizing potentials (GDPs), in rat hippocampal slices during the f...