OBJECTIVES Elevated homocysteine has emerged as a risk factor for cognitive impairment even in healthy elderly persons. Reduced brain volume and white matter hyperintensities also occur in healthy elderly as well, but the interrelationships between these have not been well studied. We report these interrelationships in non demented, relatively healthy, community-dwelling older adults from a sin...

BACKGROUND/PURPOSE Autoimmune thyroiditis can be diagnosed by measuring patients' serum levels of thyroid stimulating hormone (TSH), anti-thyroglobulin antibody (TGA), and anti-thyroid microsomal antibody (TMA). This study evaluated whether there were hematinic deficiencies, high blood homocysteine levels, and serum gastric parietal cell antibody (GPCA) positivity in patients with TGA or TMA. ...

Hyperhomocysteinaemia and hypertension are established cardiovascular risk factors for diseases. However, knowledge on the contributions of these in diabetic patients is limited. The purpose this study was to assess serum homocysteine concentrations blood pressures Type 2 Zaria, Kaduna State, Northern Nigeria. In cross-sectional study, levels were assessed 140 men women with type diabetes aged ...

BACKGROUND Homocysteine and pro-inflammatory mediators such as cyclooxygenase-2 (COX-2) have been linked to vascular dysfunction and risks of cardiovascular diseases. Fulvic acid (FA), a class of compounds of humic substances, possesses various pharmacological properties. However, the effect of FA on inflammatory responses of the monocytes remains unclear. We investigated the regulatory effect ...

Nitrous oxide (N 2 O) is an inhaled anesthetic drug that uses during surgery and recently proposed as a treatment for mood disorder in research setting. Exposure to N2O can cause hematopoietic neural side effects. The purpose of this study was the designation serum cobalamin, homocysteine CBC factors changes after exposure nitrous orthopedic surgery. This has been done on 30 patients undergoing...

introduction: increased levels of certain markers like fibrinogen and homocysteine are independently associated with an increased risk of cardiovascular diseases. considering the numerous favorable effects of healthful nutrition and physical activity on reducing the risk of atherosclerosis, in this study we intend to take into account fasting and physical activity during the month of ramadan an...

BACKGROUND Vitiligo is a chronic skin disorder. White macules caused by melanocyte destruction is a characteristic finding that cosmetically disturbing. Until recently, pathogenesis of vitiligo is still unclear. The role of homocysteine in vitiligo is mentioned in previous studies thus it is probable that it can be a biomarker to determine vitiligo severity. AIM To determine correlation betwe...

AIM Cardiovascular diseases are leading cause of death in patients with chronic renal failure. The aim of our study was to establish connection between levels of homocysteine and traditional and nontraditional risk factors for developing cardiovascular diseases in dialysis and pre dialysis patients. METHODS We included 33 pre dialysis (23 in stage three and 10 in stage four of chronic kidney ...

BACKGROUND High concentrations of homocysteine have been linked to a greater risk of Alzheimer disease, dementia, and cognitive decline. OBJECTIVE We evaluated the association between homocysteine and 4.5-y combined incidences of dementia and cognitive impairment without dementia (CIND) in a cohort of 1779 Mexican Americans aged 60-101 y. DESIGN Homocysteine, red blood cell (RBC) folate, an...