Critical signals for erythroblast formation are transduced by activated, tyrosine-phosphorylated erythropoietin receptor (EpoR) complexes. Nonetheless, steady-state erythropoiesis is supported effectively by EpoR alleles that are deficient in cytoplasmic phosphotyrosine sites. To better define core EpoR action mechanisms, signaling capacities of minimal PY-null (EpoR-HM) and PY343-retaining (Ep...

BACKGROUND A clinical randomized trial was performed to determine whether a simple homemade wound vacuum-dressing system (HM-VAC) is a feasible alternative to the use of conventional saline-soaked gauze dressings (WET) for the treatment of complex wounds in a resource-poor hospital. METHODS Forty patients were analyzed to compare the HM-VAC and the WET dressings. The HM-VAC was assembled with...

The objective of this study was to test whether the gastrointestinal tolerance of a new infant formula equalled or exceeded the tolerance of other milk-based infant formulas, and to compare the tolerance of the new formula to that of human milk. This prospective, observational, multicenter, open-label study was conducted in Taiwan. Healthy, full-term infants aged 28-98 days were enrolled on the...

For each natural number m ≥ 3, we give a rootfinding method Hm, with cubic order of convergence for simple roots. However, for quadratic polynomials the order of convergence of Hm is m. Each Hm depends on the input, the corresponding function value, as well as the first two derivatives. We shall refer to this family as Halley Family, since H3 is the well-known method of Halley. For all m ≥ 4, t...

Constraint{based types provide a formal foundation for many varieties of architectural analysis. A software architecture, typically deened using an Architecture Deenition Language (ADL), exposes the overall structure of a complex system in a way that allows validation and computation of overall system properties. We argue that the HM(X) type system can be used to implement many analyses in a si...

Hierarchical modulation (HM) is able to provide different levels of protection for data streams and achieve a rate region that cannot be realized by traditional orthogonal schemes, such as time division (TD). Nevertheless, criterions and algorithms for general HM design are not available in existing literatures. In this paper, we jointly optimize the constellation positions and binary labels fo...

Hydatidiform mole (HM) is the product of an aberrant human pregnancy in which there is an abnormal embryonic development and proliferation of placental villi. The incidence of HM varies between ethnic groups, and occurs in 1 in every 1500 pregnancies in the USA. All HM cases are sporadic, except for extremely rare familial cases. The exact mechanisms leading to molar pregnancies are unknown. We...

Fatty acids (FA), phospholipids (PL), and gangliosides (GD) play a central role in infant growth, immune and inflammatory responses. The aim of this study was to determine FA, PL, and GD compositional changes in human milk (HM) during lactation in a large group of Chinese lactating mothers (540 volunteers) residing in Beijing, Guangzhou, and Suzhou. HM samples were collected after full expressi...

Novel hybrid magnetic cross-linked enzyme aggregates of phenylalanine ammonia lyase (HM-PAL-CLEAs) were developed by co-aggregation of enzyme aggregates with magnetite nanoparticles and subsequent crosslinking with glutaraldehyde. The HM-PAL-CLEAs can be easily separated from the reaction mixture by using an external magnetic field. Analysis by scanning electron microscopy (SEM) and confocal la...

Although many studies have been conducted on the components present in human breast milk (HM), research on the differences of chemical metabolites between HM, bovine milk (BM) and formula milk (FM) is limited. This study was to explore the chemical diversity of HM, BM and FM by metabolomic approaches. GC-TOFMS and UPLC-QTOFMS were applied to investigate the metabolic compositions in 30 HM sampl...