The goal of this study is to contribute to discussions about age-related changes in electroencephalogram (EEG) complexity. Eight characteristics of complexity were evaluated for sleep EEG of 175 healthy subjects. The complexity of the sleep EEG significantly increased up to the age of about 60 years. Over 60 years, the complexity stagnated or slightly decreased. The same tendencies were manifes...

A whole body indirect calorimeter provides accurate measurement of energy expenditure over long periods of time, but it has limitations to assess its dynamic changes. The present study aimed to improve algorithms to compute O(2) consumption and CO(2) production by adopting a stochastic deconvolution method, which controls the relative weight of fidelity to the data and smoothness of the estimat...

The sleeping neocortex shows nested oscillatory activity in different frequency ranges, characterized by fluctuations between "up-states" and "down-states." High-density neuronal ensemble recordings in rats now reveal the interaction between synchronized activity in the hippocampus and neocortex: Electroencephalographic sharp waves in the hippocampus were more probable during down-states than d...

OBJECTIVE Evaluate the efficacy of ramelteon, an MT/1MT2-receptor agonist, for the treatment of transient insomnia in healthy adults. DESIGN Randomized, double-blind, placebo-controlled design using a model of transient insomnia related to sleeping in a novel environment. SETTING Fourteen sleep research centers. PARTICIPANTS Healthy adults (N=375; 228 women), aged 35 to 60 years, who had ...

This study presents data on some phasic EEG phenomena regulary recorded during sleep - wakefulness cycle and heterogeneity of EEG sleep stages forming consecutive human sleep macrocycles. These short-term EEG changes quite often tend to periodization, especially during initial sleep-stages and transitive states (sleep microcycles). An attempt was made to reveal EEG microstructures in sleep - wa...

In his seminal book on the historical periods of Western attitudes toward death, Philippe Aries describes four consecutive periods through which these attitudes evolved and transformed. According to him, the historical attitudes of Western cultures have passed through four major parts described above: "Tamed Death," One's Own Death," "Thy Death," and "Forbidden Death." This paper, after explori...

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