with establishment of a separate Department of Endocrinology. Dr Sekso first gathered a team consisting of young, gifted and enthusiastic physicians; then he organized the department, polyclinic and diabe-tological service; as early as 1970 he gathered a team of young laboratory engineers and established the laboratory of endocrinology. Thus, modern endocrinology started developing at our Hospi...

This paper reviews natural language processing (NLP) from the late 1940's to the present, seeking to identify its successive trends as these reflect concerns with different problems or the pursuit of different approaches to solving these problems and building systems as wholes. The review distinguishes four phases in the history of NLP, characterised respectively by an emphasis on machine trans...

Healthcare professionals have long been concerned with the assessment of human gait, but only recently were they able to utilize instrumental gait analysis in routine clinical practice for diagnosis, and to guide the selection of treatment methods for complex musculo-skeletal and neurological disorders. The development of motion analysis systems has progressed through several stages from simple...

The examination of birth asphyxia from a historical perspective presents several intriguing problems. First, of course, there is no satisfactory definition. Clinicians, biochemists and pathologists all seem to use the phrase, but a universal definition is lacking. Dr. Eastman of Hopkins called asphyxia "an infelicity of etymology" since the Greek derivation of asphyxia meant "without pulse." A ...

Surgery on inferior oblique muscle has a long history and various surgical techniques have been developed. The historical review of the surgery starting in 1840's to date is performed. The surgical effectiveness between simple myectomy and recession is still controversial.

Determining the velocity of meteoroids as they enter the Earth’s atmosphere is very important since the value is fundamental in calculating the orbit of the meteoroid and hence eventually its origin. We describe early attempts at this determination and highlight problems that exist today.

The objective of this chapter is to present a historical review of the field of irreversible electroporation (IRE) in the context of its medical applications. Although relevant scientific observations were made since the 18 th century, the electroporation phenomenon was not identified as an increase of membrane permeability until mid 20 th century. After that, multiple applications of reversibl...

The search for the components of the platelet surface that mediate platelet adhesion and platelet aggregation began for earnest in the late 1960s when electron microscopy demonstrated the presence of a carbohydrate-rich, negatively charged outer coat that was called the "glycocalyx." Progressively, electrophoretic procedures were developed that identified the major membrane glycoproteins (GP) t...

Adaptation to extrauterine life involves the newborn infant in a series of biological adjustments to a totally new set of environmental conditions. Prime among these is the accommodation to a thermal environment that, in all but the most tropical countries, represents a distinctly "cold" challenge. The failure to accommodate to this cold stress has historically been recognized as perhaps the ea...