Eosinophilic granuloma of bone is a destructive osseous lesion characterized by large number of histiocytes. It is classified as one of the triad of nonlipid reticuloendothelial disorders, the Langerhans cell histiocytosis (LCH). The clinical manifestation varies from a localized lesion (eosinophilic granuloma) to a systemic disease. Typically, there is bone involvement and less frequently lesi...

Background: Traumatic ulcerative granuloma with stromal eosinophilia (TUGSE) is a benign chronic ulcerative lesion of the oral mucosa of an unclear pathogenesis characterized by a mixed infiltrate of inflammatory cells including large mononuclear cells, lymphocytes and eosinophils. This study was designed to find any possible correlation between the number of different cells infiltrates and the...

OBJECTIVE To determine the pattern of occurrence of sarcomas afflicting the neck and craniofacial region. DESIGN A retrospective study (1982-1991). SETTING Cancer Registry, Kenyatta National Hospital, Nairobi, Kenya. METHOD Examination was performed of the cancer records in the registry over the period 1982 to 1991 inclusive. Histopathological types of the sarcomas were then analysed to i...

BACKGROUND This study evaluated the clinical significance of podoplanin and vascular endothelial growth factor-C (VEGF-C) expression in oral squamous cell carcinoma (OSCC). PATIENTS AND METHODS The immunohistochemical expression of podoplanin and VEGF-C were investigated in 42 well-differentiated OSCCs. The Chi-square test was used to analyze the association of biomarker expression with the c...

Histopathological malignancy grading of human gliomas is limited by subjective interpretation of the morphological criteria. Assessment of mitotic activity is a cornerstone of grading these tumours, but mitotic figures can be hard to identify in haematoxylin-eosin stained sections. Thus, determining proliferative activity by means of Ki-67/MIB-1 immunostaining has become a useful supplement. Ho...

Clear cell sarcoma of the kidney (CCSK) is an uncommon renal neoplasm of childhood. It represents between 2% and 9% of all pediatric renal tumors, and generally arises before the age of 5 years. It often mimics other pediatric renal tumors. Presently described is the case of a 7-year-old girl who presented with complaints of vomiting and abdominal pain. Abdominal ultrasonography revealed a righ...

Early detection and prognosis of breast cancer are feasible by utilizing histopathological grading of biopsy specimens. This research is focused on detection and grading of nuclear pleomorphism in histopathological images of breast cancer. The proposed method consists of three internal steps. First, unmixing colors of H&E is used in the preprocessing step. Second, nuclei boundaries are extracte...

Primary benign fibrous histiocytoma involving the central nervous system is an exceedingly rare tumor with most cases originating from the dura or parenchymal tissue. Diagnosis of primary benign fibrous histiocytoma is difficult due to its confusing histopathological characteristics. Two cases of primary intracranial benign fibrous histiocytoma mimicking parasagittal meningioma are presented in...

Background It is well known that the DCM patients having Late Gadolinium Enhancement at Mid-layer of LV septal wall (Mid-LGE) shows poor prognosis compared to the case not having Mid-LGE However, about the other histopathological differences by the existence of Mid-LGE, it is not clear. On the other hand, in recent years, it became possible to calculate ECV from measurement of T1 value of the m...

introduction: different oral lesions have clinical characteristics which in some cases are similar. therefore, in these cases histopathological examination for correct diagnosis is necessary. the aim of this study was to evaluate the compatibility rate of clinical and histopathological diagnosis of oral lesions in zahedan school of dentistry. methods: in this retrospective study, determination ...