A 37-year-old Caucasian woman presented with a blind left eye and granulomatous panuveitis in the right eye. There was a subretinal neovascular membrane with haemorrhage beneath the macula and widespread subretinal lesions that were interpreted as choroidal granulomas in the right eye. A chest x-ray that showed diffuse pulmonary fibrosis without hilar lymphadenopathy was the only contributory c...

AIMS To investigate the pathological effects of preoperative chemotherapy on oesophageal carcinoma. METHODS Qualitative and quantitative changes in oesophageal carcinoma after preoperative chemotherapy were assessed by examination of biopsy specimens before treatment and resected specimens. RESULTS Of 13 patients with adenocarcinoma treated with 5-fluorouracil, adriamycin, and mitomycin (FA...

AIMS The effect of transpupillary thermotherapy (TTT) on human choroidal melanomas was investigated by means of histopathology. METHODS Before enucleation TTT was performed in 11 eyes with a xenon are photocoagulator with a red filter or a diode laser at 810 nm. The exposure time was 1 minute; the estimated temperature at the top of the tumour was about 65 degrees C. RESULTS Seven of 11 tum...

The histopathological findings in five post-mortem eyes with anterior chamber and iris fixation intraocular lenses (IOLS) are discussed. The interval between lens insertion and death ranged from 3 1/2 to 52 months. Clinically the lenses were well tolerated and the surgery was considered to be successful. In one case a vitrectomy was required. Prominent histopathological features included reduce...

BACKGROUND IgA nephropathy, a prevalent disease in Asia, is considered the main cause of end stage renal disease among primary glomerular disease. OBJECTIVE To determine the frequency of different clinical, histopathological and immunofluorescent characteristics of IgA nephropathy. METHODS Renal biopsies of 376 patients were received for immunofluorescent and for histopathological studies. ...

BACKGROUND Celiac disease (CD) is an immune-mediated enteropathy triggered by the ingestion of gluten in genetically susceptible subjects. Although the small intestinal mucosa is the main site of the gut's involvement in CD, other mucosal surfaces belonging to the gastrointestinal tract and the gut-associated lymphoid tissue are known to be affected. AIM Assuming that the oral mucosa could re...

A benign cartilaginous tumor, chondroma, occurred in a 3.5 year-old ewe that was presented to the Veterinary Teaching Hospital, College of Agriculture and Veterinary Medicine, Qassim University. The tumor mass was in the form of a massive hard swelling at the right shoulder region. The ewe was not able to bear weight on the right forelimb that was abducted laterally. Exploration of that swellin...

BACKGROUND Sweet's syndrome refers to a set of cutaneous, systemic and histopathological alterations that occur in response to different stimuli, in a similar way to that occurring in erythema nodosum, erythema multiforme and leukocytoclastic vasculitis. The syndrome has been described in association with conditions such as infections, pregnancy, the use of certain medications and malignancy. ...

BACKGROUND A rare variant of Leishmaniasis is Localized Leishmania Lymphadenitis which has been occasionally reported from south-eastern parts of Iran. So far, no molecular assay has been performed for diagnosing this variety of Leishmaniasis. METHODS Nineteen lymph node paraffin blocks were collected from 1994 to 2007. Parasite load count and histopathological patterns reported on Hematoxyli...

OBJECTIVES To describe the histopathological features of pleomorphic adenoma (PA) with special reference to the epithelial and mesenchymal components. STUDY DESIGN 189 PA were selected and classified as myxoid or stroma-rich, cellular or cell-rich and classic (balanced amount of epithelial and stromal components). The epithelial component was analyzed according to the presence of plasmacytoid...