Isoforms of ankyrin (ankyrinsR) immunologically related to erythrocyte ankyrin (ankyrinRo) are associated with distinct neuronal plasma membrane domains of functional importance, such as cell bodies and dendrites, axonal hillock and initial segments, and nodes of Ranvier. AnkyrinRo is expressed in brain, and accounts for at least one of the ankyrinR isoforms. Another ankyrin isoform of brain, a...

Layer V pyramidal cells of the somatosensory cortex operate with two spike initiation zones. Subthreshold depolarizations are strongly attenuated along the apical dendrite linking the somatic and distal dendritic spike initiation zones. Sodium action potentials, on the other hand, are actively back-propagating from the axon hillock into the apical tuft. There they can interact with local excita...

AIM To determine the stimulation site of both facial and hypoglossal nerves after transcranial magnetic stimulation. METHODS After surgical exposure of the brainstem in 22 patients with intrinsic pontine (n=9) or medullary (n=13) tumors, the facial colliculus and the hypoglossal triangle were electrically stimulated. The EMG responses were recorded with flexible wire electrodes from the orbic...

It was recently shown that the persistent Na(+) current (I(NaP)) is generated in the proximal axon in response to somatic depolarization in neocortical pyramidal neurons, although the involvement of I(NaP) in spike initiation is still unclear. Here we show a potential role of I(NaP) in spike initiation of primary sensory neurons in the mesencephalic trigeminal nucleus (MTN) that display a backp...

As an important area of reserve land resources, the Yellow River Delta is faced with the problem of soil salinization. Grasping the characteristics of soil salinity as well as its spatial variation patterns is an important foundation of prevention, control and utilization of saline soil. This study selected Kenli County of the Yellow River Delta, obtained soil salinity data through field survey...

It has recently been shown that the persistent Na current (INaP) is generated in the proximal axon in response to somatic depolarization in neocortical pyramidal neurons, while the involvement of INaP in spike-initiation is still unclear. Here we show a potential role of INaP in spike-initiation of primary sensory neurons in the mesencephalic trigeminal nucleus (MTN) that display a backpropagat...

A systematic set of stress-temperature measurements using the laser-scanning wafer curvature technique is performed to examine the effect of passivation thickness and passivation material on stress evolution and yield properties of passivated Al films during thermal cycling for twenty cycles. A modification of Stoney's equation for multiple films on a substrate is utilized to separate the indiv...

The impact of uncontrolled municipal solid waste disposal 3800 tons per day on surface and groundwater downstream the Jawaharnagar dumping site was studied. un-engineered yard spreading over about 300 hectares (ha) is located topographic high (hillock) falls in Madyala stream Dammaiguda watersheds Musi sub-basin. Granites Archaean age underlie area. Both samples, collected covering hydrological...

(1) The application of the Nissl method to the study of the motor cells of the spinal cord, and the nerve cells of the dorsal root ganglia in typhoid fever, shows that these cells regularly suffer pathological changes in the course of the infection. (2) The alterations in the motor cells are more constant and of a severer grade than are those in the cells of the sensory ganglia. The more charac...