Concern over the neurotoxic effects of chronic moderate exposures to manganese has arisen due to increased awareness of occupational exposures and to the use of methylcyclopentadienyl manganese tricarbonyl, a manganese-containing gasoline antiknock additive. Little data exist on how the oxidation state of manganese exposure affects toxicity. The objective of this study was to better understand ...

Manganese represents an essential trace element that is accumulated and utilized by virtually all forms of life. This redox active metal is a key cofactor for a wide range of metalloenzymes, including oxidases and dehydrogenases, DNA and RNA polymerases, kinases, decarboxylases, and sugar transferases (11, 25). In addition to serving as an essential nutrient, manganese can also be toxic. In hum...

Manganese is an essential trace element which is toxic in high doses. Over the past several decades, manganese has replaced lead as the anti-knock agent in gasoline, raising concern about air and road-side contamination with this element. In addition, manganese is absorbed by the liver, making specific populations (e.g., pregnant women, infants and children, and patients with liver disease) sus...

High exposure of manganese is suggested to be a risk factor for many lung diseases. Evidence suggests anticancerous and antiangiogenic effects by products derived from Morinda citrifolia (noni) fruit. In this study, we investigated the effect of noni fruit juice (NFJ) on the expression of HIF-1α, a tumor angiogenic transcription factor in manganes...

The reactions of manganese(III) porphyrin complexes with terminal oxidants, such as m-chloroperbenzoic acid, iodosylarenes, and H(2)O(2), produced high-valent manganese(V)-oxo porphyrins in the presence of base in organic solvents at room temperature. The manganese(V)-oxo porphyrins have been characterized with various spectroscopic techniques, including UV-vis, EPR, 1H and 19F NMR, resonance R...

The paper describes the development of austenitic steel with TWIP effect, which is alloyed chromium to increase corrosion resistance. experimental heat this was cast in an melting furnace and subsequently subjected hot cold rolling. After rolling, appropriate recrystallization annealing temperature applied obtain optimal grain size. X-ray diffraction proved that contains a fully structure. anne...