in order to perform a histomorphometric study of blood cells in male adult ostrich, blood samples were obtained from jugular vein of 10 clinically healthy male adult ostriches (2 - 3 years old). the slides were stained with the giemsa methods and the smears were evaluated for cellular morphology, with cellular size being determined by micrometry. the findings of this study revealed that the sha...

objective(s): electrospun nanofibrous mats of poly(lactic acid) (pla) and nanohydroxyapatite (nano-ha) were prepared and proliferation and differentiation of mesenchymal stem cells on the prepared nanofibers were investigated in this study. materials and methods: pla/nano-ha nanofibers were prepared by electrospinning. the effects of process parameters, such as nano-ha concentration, distance, ...

introduction: constipation is one of the most common complaints of individuals, which may present with complication like hemorrhoid and fissure. hirschsprung is a disease presenting with chronic constipation and its diagnosis may be delayed until adulthood. it is diagnosed by biopsies from anorectal transitional zone. this study aimed to evaluate the association between hirschsprung and anorect...

a common pathological process that occurred after brain injury is gliosis. gliosis involves the activation of glial cells to proliferate and become hypertrophic to occupy the injured brain areas. in order to form a defense system against the invasion of micro-organisms and cytotoxins into surrounding tissue, glial cells including astrocytes and microglia undergo reactive response to injury. neu...

objective(s)progesterone is a steroid hormone whose biology has been greatly studied within the confines of reproductive function. in recent years, the neuroprotective effects of progesterone have attracted growing interest. glial cell line-derived neurotrophic factor (gdnf), is a neurotrophic factor which plays a crucial role in the development and maintenance of distinct sets of central and p...

objective(s): the aim of this study was to determine the important molecules involved in apoptosis induction by opium in jurkat cell line. materials and methods: jurkat cells were incubated 48 hrs with2.86×10-5 g/ml concentration of opium and apoptosis as well as expression levels of related molecules weremeasured. results: our results demonstrated that 50.3±0.2 percent of opium treated jurkat ...

in the development of neuroinflammatory diseases, alterations of the blood brain barrier (bbb) represent key events. the integrity of the bbb is partially maintained by endothelia cells (ecs), since they actively limit the transmigration of immune cells. however, the factors that cause endothelial cells to develop an immune cell-permissive phenotype are poorly understood. in general, it has bee...

background: langerhans' cell histiocytosis (lch) is a reactive proliferative disease of unknown pathogenesis characterized by proliferation of langerhans cells. involvement of bone marrow (bm), liver and lung are related to high risk factors and poor survival. the aim of this report is to highlight the clinical and haematological findings of 5 cases of lch with bm infiltration which may help to...

primary and secondary malignant central nervous system (cns) tumors are devastating invasive tumors able to give rise to many kinds of differentiated tumor cells. glioblastoma multiform (gbm), is the most malignant brain tumor, in which its growth and persistence depend on cancer stem cells with enhanced dna damage repair program that also induces recurrence and resists current chemo- and radio...

background: natural killer (nk) cells are the effector cells of innate immunity that respond to infection and tumor. interactions between killer cell immunoglobulin like receptors (kir) and human leukocyte antigen (hla) class i molecules regulate nk cells responses to eliminate infected and transformed cells. objective: to investigate the impact of kir genes, hla ligand genes, and kir-hla combi...