Infection of Human Enterovirus (HEV) containing coxsackievirus has been associated with wide variety clinical illnesses, including aseptic meningitis and central nervous system pathologies. Although diagnosis of HEV infection relies on detection of the virus in the Cerebrospinal fluid (CSF), the virus loads in such specimens tend to be quite low. To improve the sensitivity of HEV diagnosis, the...

conclusions the analysis indicates that the hev isolated from blood donors in the southwest of iran belongs to genotype 1. however, more samples from other geographic regions of iran are needed to confirm these findings. because transmission of hev by administration of blood or blood components is likely to occur, it may be sensible to screen donor blood for hev to eliminate transfusion-transmi...

Specific-pathogen-free pigs were inoculated with one of two hepatitis E viruses (HEV) (one recovered from a pig and the other from a human) to study the relative pathogenesis of the two viruses in swine. Fifty-four pigs were randomly assigned to three groups. Seventeen pigs in group 1 served as uninoculated controls, 18 pigs in group 2 were intravenously inoculated with the swine HEV recovered ...

Hepatitis-splenomegaly (HS) syndrome is an emerging disease in chickens in North America; the cause of this disease is unknown. In this study, the genetic identification and characterization of a novel virus related to human hepatitis E virus (HEV) isolated from bile samples of chickens with HS syndrome is reported. Based upon the similar genomic organization and significant sequence identity o...

HEV is one of the most important causes of acute clinical hepatitis in adults with particularly high mortality in pregnant women in developing countries, such as China.1 Although low seroprevalence of HEV infection in pregnant women was reported in Kunming City, Yunnan Province, China in 2011,2 an outbreak of HEV occurred in the city in 2015 affecting both pregnant women and general population....

Hepatitis E virus (HEV), the causative agent of hepatitis E, is an important human pathogen. Increasing evidence indicates that hepatitis E is a zoonosis. Avian HEV was recently discovered in chickens with hepatitis-splenomegaly syndrome in the USA. Like swine HEV from pigs, avian HEV is also genetically and antigenically related to human HEV. The objective of this study was to construct and ch...

Hepatitis E virus (HEV) is a single-stranded, positive-sense RNA virus in the family Hepeviridae. Hepatitis E caused by HEV is a clinically important global disease. There are currently four well-characterized genotypes of HEV in mammalian species, although numerous novel strains of HEV likely belonging to either new genotypes or species have recently been identified from several other animal s...

BACKGROUND In the last decade hepatitis E virus (HEV) is increasingly recognized as a cause of acute viral hepatitis in developed countries. HEV is transmitted via the fecal-oral route. In countries like the Netherlands, HEV infection is suspected to be a zoonosis but HEV may also be introduced by migrants. We studied the seroprevalence of HEV among different migrants, mainly Moroccans and Turk...

Submit Manuscript | http://medcraveonline.com Hepatitis E virus (HEV) infection among humans is sporadic in European countries. Nevertheless, cases of HEV infection, either imported or autochthonous, have been reported from many countries, including Spain [1,2]. With a single exception [3], autochthonous cases reported from Europe were always due to HEV genotype 3 (HEV-3), which has been found ...

We evaluated the prevalence of hepatitis E virus (HEV) in the pork production chain in Czech Republic, Italy, and Spain during 2010. A total of 337 fecal, liver, and meat samples from animals at slaughterhouses were tested for HEV by real-time quantitative PCR. Overall, HEV was higher in Italy (53%) and Spain (39%) than in Czech Republic (7.5%). HEV was detected most frequently in feces in Ital...