OBJECTIVE To verify or refute the value of hospital episode statistics (HES) in determining 30 day mortality after open congenital cardiac surgery in infants nationally in comparison with central cardiac audit database (CCAD) information. DESIGN External review of paediatric cardiac surgical outcomes in England (HES) and all UK units (CCAD), as derived from each database. SETTING Congenital...

Hypertonic and hyperoncotic solutions are generally used as acute treatment for symptomatic hypotension during dialysis. Administration of hydroxyethylstarch (HES) was recently shown to be an effective substitution fluid in preserving blood volume (BV) and systolic BP (SBP) in a group of stable dialysis patients during dialysis. In this study, in nine cardiac-compromised dialysis patients with ...

OBJECTIVE To investigate effect of equal volumes (250 ml) of 7.2% hypertonic saline - 6% hydroxyethyl starch (HS-HES) and 20% mannitol (M) on dural tension, serum osmolality and hemodynamics in patients during elective neurosurgical procedures. MATERIAL AND METHODS Forty ASA I-II patients scheduled for elective neurosurgical supratentorial procedures were randomly assigned to two groups. Abou...

BACKGROUND Plasma expanders are commonly used in the management of critically ill patients, which may exhibit altered hemorheology. We evaluated the effects of various synthetic colloids and Lactated Ringer's (LR) solution on hemorheological parameters in vitro and in a rodent hemorrhagic shock model. METHODS For the in vitro experiments, rat blood was incubated with hydroxyethyl starch (HES)...

The HydroCoil Embolic System (HES; MicroVention, Aliso Viejo, CA) was developed to improve the efficacy of endovascular treatment of cerebral aneurysms. The HES may reduce recurrences of aneurysms by allowing for increased packing density as compared with platinum coils. We report our initial experience with the HES in the treatment of 11 patients with cerebral aneurysms and compare findings to...

Hypereosinophilic syndrome (HES) is a condition with diverse clinical presentation and prognosis. Due to its rarity, it often under-recognized. We present 48-year-old female patient who presented eosinophilic pneumonia bullous pemphigoid; rare skin manifestation of HES. It was considered as primary HES after comprehensive evaluation excluded secondary causes. However, picture laboratory makers ...

BACKGROUND Intravascular volume replacement is often required in the presence of increased pulmonary capillary leakage, for example in patients with volutrauma with major hemorrhage. In the present study, the effects of Ringer's acetate (RA), gelatin-polysuccinate (GEL), and a modern hydroxyethyl starch (HES, 6% 130/0.42) on lung and kidney function and damage were compared in a two-hit model o...

Human embryonic stem (hES) cells, due to their capacity of multipotency and self-renewal, may serve as a valuable experimental tool for human developmental biology and may provide an unlimited cell source for cell replacement therapy. The purpose of this study was to assess the developmental potential of hES cells to replace the selectively lost midbrain dopamine (DA) neurons in Parkinson's dis...

We present the quantitative methods used for selecting candidate metal-poor stars in the Hamburg/ESO objective-prism survey (HES). The selection is based on the strength of the Ca ii K line, B − V colors (both measured directly from the digital HES spectra), as well as J − K colors from the 2 Micron All Sky Survey. The KP index for Ca ii K can be measured from the HES spectra with an accuracy o...