autoimmune lymphoproliferative syndrome (alps) is a rare inherited disorder of apoptosis. it usually presents with chronic lymphadenopathy, splenomegaly, and symptomatic cytopenia in a child. herein, we report a 14-year-old boy with symptoms misdiagnosed as hemophagocytic lymphohistiocytosis who was treated before alps was diagnosed for the patient. this case should alert pediatricians to consi...

herein, we report a patient with arterio-venous fistula secondary to mycotic aneurysm, causing high output heart failure. the patient had one-year history of refractory heart failure and recurrent pulmonary edema. this presentation is a good example of curative surgically treatable cause of high-output congestive heart failure. iran j med sci 2005; 30(1): 41-44.   keywords ● arterio-venous fist...

myiasis is an infestation of tissues with larval stage of dipterous flies.  this condition most often affects the skin and may also occur in certain body cavities.  it is mainly seen in the tropics, though it may also be rarely encountered in non-tropical regions.  herein, we present a case of cutaneous furuncular myiasis in an iranian male who had travelled to africa and his condition was fina...

herein we report a case of primary leiomyosarcoma of testis, which was believed to originate from normal testicular structures.  it contained smooth muscle cells, blood vessels and contractile cells of the seminiferous tubules.  no evidence of tumor spread was found. treatment consisted of orchiectomy with high ligation of the spermatic cord.  the patient received no adjuvant therapy and there ...

intraventricular tuberculoma (ivt) is extremely rare, ct and mri patterns have been only sparsely described.  herein, a case of intraventricular tuberculoma in a 40 year-old woman is reported.  at admission, the patient displayed malaise and was confused and deteriorated suddenly.  brain ct and mri findings were very similar to intraventricular meningioma.  the patient underwent surgery and tub...

incontinentia pigmenti (ip) is an uncommon x-linked dominant genodermatosis characterized by four cutaneous stages and frequent association with dental (90%), central nervous system (33%) and ocular (35%) anomalies. the exact pathogenesis of this disorder remains unknown. herein, we report a newborn girl with inflammatory vesiculobullous and warty skin lesions and a positive family history of i...

amelanotic melanoma is a variant of malignant melanoma comprising 2% to 8% of all malignant melanomas. the amelanotic presentation of melanoma in the oral cavity is extremely rare and has been reported only occasionally in the literature. moreover, the lack of melanin makes these tumors difficult to diagnose than that of pigmented lesions and the prognosis tends to be poorer. herein, we report ...

systemic amyloidosis is a very rare complication of inflammatory bowel disease (ibd). the reported cases of secondary amyloidosis in children with ibd are much fewer than those reported in adults. herein, a teenage boy with crohn’s disease is presented who developed nephrotic syndrome due to renal involvement secondary to amyloidosis, whereas the patient was under treatment with corticosteroid ...

multiple primary tumors in a single patient are relatively rare when four or more distinct lesions are considered. herein, we report a case of woman with four different primary tumors: meningioma, renal angiomyolipoma, spinal ependymoma and high-grade soft tissue sarcoma. there was no family history and hereditary syndrome. the genetic analysis was completely normal. to best of our knowledge, t...

Chordomas are low-grade malignant tumors of bone that occur almost exclusively in the axial  skeleton. Chordomas are rare in children and adolescents and comprise <5% of all cases and the  site of development is at the skull base. These tumors are believed to behave more aggressively  than chordomas in adults and may have unusual morphology. We herein present a rare case of chordoma in a 20-yea...