BACKGROUND During the past three decades, the incidence of hepatocellular carcinoma in the United States has tripled. The neuroendocrine character has been observed in some tumor cells within some hepatocellular carcinoma nodules and elevated serum chromogranin A also been reported in patients with hepatocellular carcinoma. The aim of this work was to investigate the role of serum concentration...

OBJECTIVE Hepatocellular carcinoma is one of the most aggressive cancers with poor prognosis worldwide. Tumor progression remains a significant cause of high mortality in patients with hepatocellular carcinoma. However, the molecular mechanism underlying tumor progression of hepatocellular carcinoma has not been completely unraveled currently. The aim of this study was to gain insight into the ...

We discuss an NNLO realization of the general mass scheme S-ACOT-χ for treatment of heavy-flavor production in neutral current deep-inelastic scattering. The connection of this scheme to the QCD factorization theorem with massive quarks is elucidated. As a new feature, kinematical constraints on collinear production of heavy quarks that are crucial near the heavy-quark threshold are included in...

The polymer stabilized state of ferroelectric liquid crystals (FLC) is reviewed; and the effect of a dispersed polymer network in an FLC outlined and discussed. All fundamental material aspects are demonstrated; such as director tilt angle; spontaneous polarization; response time and viscosity; as well as the dielectric modes. It was found that the data can largely be explained by assuming an e...

Sudan I is generally considered mutagenic based on various in vitro and in vivo tests and is carcinogenic in the rat. Dose-response modelling of the data for hepatocellular adenomas in male rats gave a BMDL(10) of 7.3mg/kg-bw/day. Sudan I is an unauthorised substance that might be present in food intermittently. The great variability and uncertainties in the human exposure data which are countr...

Plants flower in particular seasons even in natural, fluctuating environments. The molecular basis of temperature-dependent flowering-time regulation has been extensively studied, but little is known about how gene expression is controlled in natural environments. Without a memory of past temperatures, it would be difficult for plants to detect seasons in natural, noisy environments because tem...

Oncological diseases are one of the leading health problems both in world and Kazakhstan, second only to cardiovascular diseases. Hepatocellular carcinoma occupies 8th place structure oncopathologies, has an unfavorable prognosis course. According WHO, more than 1.3 million people die each year from hepatocellular (HCC). The incidence rate HCC Kazakhstan is up 5.5 cases per 100 thousand populat...

background: to glean insights into the relationship among hepatitis b virus (hbv) genotype/subgenotypes, a1762t/g1764a mutations and advanced liver disease such as liver cirrhosis (lc) and hepatocellular carcinoma (hcc) in southeast china. methods: a case-control study was performed, consisting of chronic hepatitis b (chb) patients (n=160), lc patients (n=150), and hcc patients (n=156). fluores...

background: hepatocellular carcinoma (hcc) is a primary liver cancer that frequently causes mortalities. transarterial chemoembolization (tace) is a new palliative treatment for advanced stages of hcc. in this study, we have assessed the results of tace on a group of iranian patients with advanced hcc treated at imam khomeini general hospital. materials and methods: this was a case series, coho...

conclusions this information provides an explanation for the previously valuable literature on the functions of lncrnas and suggest for the novel therapeutic targeting. results the lncrnas hottip, h19, hotair, malat1, antisense igf2r (air), hoxa13, gtl2 (also called meg3) and uc002mb have been reported in association with hcc. besides, this study predicted that eif4aiii, ptb and fus were the mo...