We report a 54-year-old patient with the association of hepatic dysfunction with cyanosis, severe hypoxemia, platypnea-orthodeoxia, diffuse cutaneous spider nevi, telangiectasia, palmar erythema, digital clubbing and findings of marked intrapulmonary vascular dilation and arterovenous shunt. The diagnosis of hepato-pulmonary-cutaneous syndrome, a term we think more appropriate and inclusive tha...

Editor’s key points † Abnormal liver function test results are common among intensive care unit patients with traumatic brain injury. † This often occurs in the absence of any pre-existing liver dysfunction. † Hepato-biliary ultrasound scans are frequently requested to exclude treatable causes. † The authors assessed the diagnostic yield of scans performed for this reason. Background. This stud...

We used a commercial enzymatic kit for measuring 7 alpha-hydroxylated bile acids to screen urines from normal subjects, liver-transplant recipients, and patients with various liver diseases, cerebro-hepato-renal syndrome, or cerebrotendinous xanthomatosis (CTX). Because of their high concentrations of 7 alpha-hydroxylated compounds excreted, the CTX patients were clearly distinguished from all ...