Essential thrombocythemia is a chronic myeloproliferative disorder characterized by a sustained proliferation of megakaryocytes, which leads to increased numbers of circulating platelets. Hemorrhagic and/or thrombotic episodes are frequent, and thrombosis of both veins and arteries may develop. Vessels in unusual sites may be involved, e.g., the hepatic veins, mesenteric veins, and the dig...

Locally advanced hepatocellular carcinoma (HCC) with portal vein thrombosis carries a 1-year survival rate <10%. Localized concurrent chemoradiotherapy (CCRT), followed by hepatic arterial infusion chemotherapy (HAIC), was recently introduced in this setting. Here, we report our early experience with living donor liver transplantation (LDLT) in such patients after successful down-staging of HCC...

Suppurativethrombophlebitis of the portal vein, or pylephlebitis, is a rare infectious manifestation. Only few casesresulting from Fusobacterium species have been reported, demonstratingthe disease that in some ways analogous to Lemierre’s syndrome, orsuppurative thrombophlebitis internal jugular vein. Of these, Fusobacteriumnucleatum represents an important subtype with unique colon cancer ris...

Objective: This study investigated the relationship between the incidence of hepatic encephalopathy (HE) after transjugular intrahepatic portosystemic shunt (TIPS) for chronic portal vein thrombosis (PVT) and the surgical procedures based on the anatomical classification of thrombosis. Methods: In the present retrospective study, 73 consecutive patients were diagnosed with chronic PVT and treat...

Patients with hepatocellular carcinoma may present with variceal bleeding as the initial symptoms. The aims of this study is to investigate the characteristics of such patients. A total of 1046 hepatocellular carcinoma cases were retrospectively retrieved from our computer records between 1980 and 1993. The medical records and image studies were reviewed. The status of each patient was assessed...

tion of splenic vein thrombosis: a novel approach to the portal venous system A diagnosis of portal system thrombosis can be easily obtained with conventional digital imaging [1]; however, the etiology of the thrombosis can be difficult to assess in the absence of the characteristic hallmarks of a malignant or benign thrombus. When a definitive diagnosis is required, transabdominal ultrasound-g...

OBJECTIVE We assessed the outcomes of a simplified technique for the percutaneous placement of a hepatic artery port-catheter system for chemotherapy infusion in advanced hepatocellular carcinoma with portal vein invasion. MATERIALS AND METHODS From February 2003 to February 2008, percutaneous hepatic artery port-catheter insertion was performed in 122 patients who had hepatocellular carcinom...

OBJECTIVE To determine the prevalence and associations of the impaired visibility of the hepatic veins (HV) on the multi-detector row computed tomography (MDCT) in cirrhotic patients. MATERIALS AND METHODS Eighty-seven consecutive cirrhotic patients undergoing triphasic liver MDCT were enrolled. The patency of the HV and the direction of the blood flow in the main portal vein, inhomogeneity o...

Fucoidan, a sulfated poly(L-fucopyranose), is an effective anticoagulant in vitro and in vivo. In the present study, an aminated derivative of fucoidan was prepared and examined for its fibrinolytic and anticoagulant activities. The aminated derivative was more potent than native fucoidan as a stimulator of tissue plasminogen activator-induced plasma clot lysis, and its effectiveness was compar...