Colorectal cancer is the second leading cause of mortality from cancer in the United States. Death from colorectal cancer usually results from metastatic disease to the liver. Complete surgical resection is the only potentially curative treatment option for metastatic colorectal cancer to the liver, with a five-year survival rate of approximately 30%-40%. The addition of adjuvant systemic or he...

As number of cancer patients increasing, the chemotherapy treatments are also increasing. This analysis aims to provide a cutting-edge outline antineoplastic medications extracted from streptomyces. Streptomyces main source antibiotic production. Antineoplastic moderate pace tumor development and postpone metastasis. The utilization performance methods discussed, with focus on drugs. produces c...

introduction: bone marrow transplantation is a good therapeutic modality for beta thalassemia. liver complications are one of the major causes of morbidity and mortality following bmt. determination of the factors of liver injury leads to earlier  diagnosis after bmt and improves prognosis. method: we studied 113 major beta thalassemic patients who have been transplanted from 1990- 2000 in bone...

background: bone marrow transplantation is a good therapeutic modality for beta thalassemia. liver complications is one of the major causes of morbidity and mortality following bmt. determination of the factors of liver injury leads to earlier diagnosis after bmt and improves prognosis. materials and methods: we studied 113 major beta thalassemic patients who have been transplanted from 1990- 2...

A screlosed hemangioma of the liver is rare among hepatic tumors. A 75 years old male was referred to our hospital for gastric cancer and a hepatic tumor. The histological finding of gastric cancer was revealed to be well differentiated adenocarcinoma. The liver tumor was 1.1×1.0 cm in size and located in segment 8 of the liver. Computed tomography (CT) showed it to be a tumor with ring enhance...

Arsenic exposure mainly through food and water has been shown to be associated with increased incidence of numerous cancers and non-cancer harmful health. It is also used in cancer chemotherapy and treatment of several cancer types due to its apoptogenic effects in the various cancer and normal cell lines. We have already reported that liver is the storage site and important target organ in As ...

The purpose of this study is to evaluate the feasibility of hepatic arterial port implantation using a 2.9-Fr coaxial microcatheter for hepatic arterial infusion chemotherapy (HAIC) in patients with unresectable hepatocellular carcinoma (HCC) in the long-term follow-up period. Our study subjects were 176 patients with unresectable HCC who underwent hepatic arterial port implantation using a 2.9...

Liver cancer or hepatic cancer is a cancer that originates in the liver. It is formed from either the liver itself or from structures within the liver, including blood vessels or the bile duct. Liver cancer can be a life-threatening condition, but it may be cured if found early. Hepatic artery embolization is one of the treatment options involving the injection of substances to reduce the blood...

PURPOSE This study aimed to identify novel biological markers for the prediction of colorectal cancer liver metastasis. EXPERIMENTAL DESIGN We established two models that mimicked the interactions between colorectal tumor cells and the liver microenvironment. From these models we established subcell lines that had an enhanced ability to metastasize to the liver. Genes that related to hepatic ...

OBJECTIVE To explore the efficacy of hepatic resection (HR) in a relatively unselected group of patients with ovarian cancer liver metastases (OCLM). METHODS A study was conducted between September 2000 and September 2011 on 60 ovarian cancer patients with hepatic metastases (24 solitary and 36 multiple), 40 of whom had extrahepatic metastases. HR was done in all patients provided that curati...