BACKGROUND Alosetron is a potent and selective 5-HT3 receptor antagonist, which has been shown to be beneficial in the treatment of female patients with non-constipated irritable bowel syndrome. AIMS To investigate the effect of alosetron on whole gut, small bowel and colonic transit in patients with irritable bowel syndrome (Study 1) and healthy volunteers (Study 2). SUBJECTS Thirteen pati...

BACKGROUND/AIMS Longtime chronic malabsorption may among other things cause a lack of liposoluble vitamins. Vitamin E deficiency can lead to formation of lipofuscin aggregates. Its deficiency is also associated with an increased lipofuscinosis of the bowel, i.e. brown bowel syndrome. METHODS Systematic research via Medline on brown bowel syndrome, lipofuscinosis, and vitamin E deficiency was ...

Both irritable bowel syndrome and endometriosis are common conditions, although symptomatic gastrointestinal endometriosis is extremely rare. We report the case of a patient initially thought to have irritable bowel syndrome, in whom the diagnosis of endometriosis only became clear following a laparotomy for small bowel obstruction. This case highlights the need to question the diagnosis in pat...

AIM The aim of this study was to assess the incidence of irritable bowel syndrome in women undergoing hysterectomy and tubular ligation. BACKGROUND The results of previous studies have shown an increased incidence of irritable bowel syndrome after gynecological surgeries. PATIENTS AND METHODS Participants were patients of Alzahra and Taleghani University hospitals in Tabriz. One hundred and...

Cowden syndrome is an uncommon, autosomal dominant disease characterized by multiple hamartomas and hyperplastic lesions in the skin, mucous membrane, brain, breast, thyroid, and gastrointestinal tract. About 30% of Cowden syndrome cases are reportedly complicated by malignant diseases. Hamartomatous polyps occur throughout the gastrointestinal tract, the most common sites being the stomach, co...

background: irritable bowel syndrome (ibs) was one of the most common functional gastrointestinal disorders. psychological treatments have been effective in reducing symptoms severity and increasing mental health and well-being of these patients to some extent. the aim of this study was to determine the effectiveness of cognitive – behavioral stress management training on symptoms severity and ...

background : this research aimed to determine the efficacy of emotion focused therapy on quality of life and sleep problems of ibs patients. materials and methods : in this research 52 ibs patients who  met this diagnosis, according the rome ii criteria, were selected and assigned to two experimental and control groups with 26 ibs patients in each group. the emotion focused therapy according gr...

aim and background: considering the high frequency of anxiety and depressive symptoms in irritable bowel syndrome (ibs) patients, selective serotonin reuptake inhibitors (ssris) are recommended by some gastroenterologists for treatment. in this study, the efficacy of fluvoxamine on severity of symptoms and quality of life in ibs patients was assessed. methods and materials: a randomized, double...

The intestine plays an important role in the processes of systemic inflammation, sepsis and multiple organ dysfunction, course hemorrhagic shock, trauma, burns, pancreatitis, extensive abdominal surgery seriously ill patients intensive care units (ICUs). One leading causes affecting outcomes treatment surgical after interventions on organs continues to be syndrome intestinal insufficiency devel...

BACKGROUND Irritable bowel syndrome is one of the most commonly encountered gastrointestinal disorders, for which there are no established diagnostic criteria. Thus, a diagnosis of IBS is made by exclusion of any organic diseases. Recently, important attempts for the positive diagnosis of irritable bowel syndrome by questionnaire surveys of physical symptoms have been made. We performed a quest...