background: hemophilia a and b are the most frequent congenital coagulation disorders. this study was conducted to determine the prevalence of hepatitis b, c and human immunodeficiency viruses among hemophilic patients in hamadan, iran. patients and methods: in this study, patients with hemophilia a and b treated in hamedan hemophilia center, hamedan, iran, were screened for hepatitis b, c and ...

Acquired hemophilia is a rare but potentially fatal clinical condition requiring clinical suspicion to reach to a diagnosis, especially in elder patients. This diagnosis should be suspected in patients that present with unexplained persistent bleeding from skin, soft tissues, and mucosa and have a prolonged aPTT.

Background: Hemophilia is a chronic bleeding disease and can interfere with daily performance of children. These children require continuous training to prevent bleeding. Since children nurses play an important role in the education of sick children and their self-efficacy and the increase use of educational computer games, the use of educational games for teaching self-efficacy to children wit...

inhibitor development is a lifelong challenge for patients with bleeding disorders who received replacement therapy. most commonly, inhibitor formation was observed in hemophilia a patients but patients with rare bleeding disorders (rbd) especially patients with deficiency of factor xiii (fxiii) and factor v (fv) can develop an inhibitor against exogenous factors. several factors considered as ...

Hemophilia is an inherited bleeding disorder caused by the lack of a protein necessary for blood clotting. Gene therapy hemophilia involves introduction healthy gene into patient's cells to produce missing protein. There are two main types hemophilia: ex vivo therapy, which extraction from patient, these in laboratory, and reintroduction modified patient; direct delivery body using viral vector...

background: hemophilia is a chronic bleeding disease and can interfere with daily performance of children. these children require continuous training to prevent bleeding. since children nurses play an important role in the education of sick children and their self-efficacy and the increase use of educational computer games, the use of educational games for teaching self-efficacy to children wit...

a group of iranian patients suffering from factor viii deficiency (hemophilia a) and treated with contaminated coagulation factor (imported), became seropositive as determined by elisa method. sixty of these individuals, which were available, were studied for abo distribution. the b blood group in anti hiv pos. individuals (13.33%) shows a significant decrease in comparison with the total (1504...

F.Giannelli, P.M.Green, K.A.High, S.Sommer, D.P.Lillicrap, M.Ludwig, K.OIek, P.H.Reitsma, M.Goossens, A.Yoshioka and G.G.Brownlee* Paediatric Research Unit, Guy's Tower, London Bridge, London SE1 9RT, UK, School of Medicine, Division of Hematology, University of North Carolina, Chapel Hill, NC 27599, Mayo Clinic, 200 Southwest First Street, Rochester, MN 55905, USA, department of Pathology, Ric...

Prophylactic treatment of haemophilia has been gaining acceptance as the optimal therapeutic option in an increasing number of haemophilia centres in the developed world in recent years. This paper focus on three aspects of prophylactic therapy: when to start treatment, venous access and the dose/dose interval. Evidence is in favour of prophylactic treatment to be started at an early age using ...

Katharine Dormandy Haemophilia Centre and Thrombosis Unit, The Royal Free and University College Medical School, London NW3 2QG, United Kingdom. Department of Haematology, Imperial College Academic Health Sciences Centre, Hammersmith Hospital, London W12 0NN, United Kingdom Department of Haematology, Royal Children’s Hospital and Royal Brisbane and Women’s Hospital, Brisbane, Queensland, Austra...