BACKGROUND Valvular heart disease is a leading cause of cardiovascular mortality, especially in China. More than a half of valvular heart diseases are caused by acute rheumatic fever. microRNA is involved in many physiological and pathological processes. However, the miRNA profile of the rheumatic valvular heart disease is unknown. This research is to discuss microRNAs and their target gene pat...

surgery for heart diseases during pregnancy, especially necessitating cardiopulmonary bypass, is believed to trigger maternal and fetal risks and should be performed only when medical therapy has been unsuccessful to alleviate the cardiac decompensation. a 33-year-old pregnant woman in her 33rd week of gestation was admitted to our hospital. she had rheumatic mitral valvular stenosis and had un...

Aortic valve disease is a fatal disease with but a single cure. Removal of the mechanical obstruction in aortic stenosis (surgery or TAVI) and replacement of an incompetent valve (so far only surgery) are the only treatment options. While aortic valve replacement in patients with isolated valve disease and normal pumpfunction of the heart has become a routine procedure and is performed with exc...

The calculated systolic, diastolic and mean pulmonary artery pressure, the ratio of sizes right left ventricles heart, eccentricity index ventricle, systolic excursion fibrous ring tricuspid valve, movement myocardium at level valve area atrium are main echocardiographic indicators for assessing idiopathic similar forms hypertension according to current Russian, Eurasian European guidelines in ...

we report a rare case of acute right coronary artery stenosis developing in a patient undergoing aortic valve replacement. we present a case report with a brief overview of the literature relating to coronary artery occlusion associated with cardiac valve surgery – the theories and treatments are discussed. a 85 year-old female was admitted under the care of the  cardiothoracic team with signs ...

Degenerative aortic valve stenosis (AS) is the most common valvular heart disease. About two-thirds of all valve operations are for aortic valve replacement (AVR). After onset of symptoms (angina, syncope or heart failure) severe aortic stenosis has a poor prognosis with an average survival of two or three years and a high risk of sudden death. According to the ACC/AHA and the European Society ...

Described herein are five patients who had double left-sided cardiac valve replacement for mitral and aortic valve stenosis resulting from two different etiologies: rheumatic heart disease, the cause of the mitral stenosis, and congenital heart disease (bicuspid valve), the underlying cause of the aortic stenosis.

High precision is necessary during percutaneous transcatheter heart valve implantation. The precision of the implantation has been established by increasing the heart rate (usually to 200 beats per minute) to the point of significantly reduced cardiac output and thus minimizing valve movement. Routinely, this tachycardia is induced by rapid pacing. Here we report a case of failure to pace durin...

Heart murmurs are a common finding during physical examination of children but most of them are innocent or normal.recognizing the etiology of heart murmurs can help us in differential diagnosis of them.the peresent study was undertaken to determine the prevalence and etiology of heart murmurs  in 4761 school children.the sex ratio was nearly 1:1 ,murmurs were heard in 459 students (9.64%) with...

We describe a case of Gemella bergeriae endocarditis in a patient with a bicuspid aortic valve. Diagnosis was confirmed by sequencing of 16S rRNA genes in heart valve tissue. This is the first report of Gemella endocarditis confirmed by molecular detection of bacterial genes in heart valve tissue.