Cold heart protection via cardioplegia administration, limits the amount of oxygen demand. Systemic normothermia with warm cardioplegia was introduced due to the abundance of detrimental effects of hypothermia. A temperature of 32-33°C in combination with tepid blood cardioplegia of the same temperature appears to be protective enough for both; heart and brain. Reduction of nitric oxide (NO) co...

The effects of schisandrin B (Sch B), curcumin, epigallocatechin gallate (EGCG) and resveratrol on the glutathione regeneration capacity (GRC) of liver and heart tissues ex vivo were examined in relation to their protective effects against CCl4 hepatotoxicity in vivo and myocardial ischemia/reperfusion (I/R) injury ex vivo in rats. Results indicated that Sch B, but not curcumin, EGCG or resvera...

WE PREVIOUSLY reported the immunological protection from humoral rejection afforded to a hamster heart that was heterotopically placed into a rat 2 months after hamster liver transplantation. Furthermore. this protection was so robust that injection of specific hyperimmune serum was unable to reverse this process. We attributed these observations to a switch of the recipient's complement (C) to...

-Protein Kinase C Activator ε -Protein Kinase C Inhibitor and δ Additive Protection of the Ischemic Heart Ex Vivo by Combined Treatment With Print ISSN: 0009-7322. Online ISSN: 1524-4539 Copyright © 2003 American Heart Association, Inc. All rights reserved. is published by the American Heart Association, 7272 Greenville Avenue, Dallas, TX 75231 Circulation doi: 10.1161/01.CIR.0000081943.93653.7...

Preservation and storage techniques represent two major issues in routine cardiac surgery and heart transplantation. Historically, these methods were conceived to prevent ischemic injury to myocardium after cardiac arrest during heart operations. Evidence shows that endothelium plays a critical role in the maintenance of normal heart function after cardiac operation, mainly by controlling the c...

Copyright © 2009 American Heart Association. All rights reserved. Print ISSN: 1941-7705. Online 7272 Greenville Avenue, Dallas, TX 72514 Circulation: Cardiovascular Quality and Outcomes is published by the American Heart Association. DOI: 10.1161/CIRCOUTCOMES.108.808469 2009; 2009;2;65-72; originally published online Mar 5, Circ Cardiovasc Qual Outcomes Heart Protection Study Collaborative Grou...

Chickens are a major source of protein worldwide, yet infectious diseases continue to threaten the poultry industry. Avian pathogenic Escherichia coli (APEC), a subgroup of extraintestinal pathogenic E. coli (ExPEC), causes colibacillosis in chickens resulting in economic loss because of treatment, condemnation of products, and death. In this study, we evaluated a recombinant antigens (rAg) vac...

background: echocardiographic evaluations of the longitudinal axis of the left ventricular (lv) function have been used in the diagnosis and assessment of heart failure with normal ejection fraction (hfnef). the evaluation of the global and segmental peak systolic longitudinal strains (pslss) by two-dimensional speckle tracking echocardiography (ste) may correlate with conventional echocardiogr...