نتایج جستجو برای: heart failure plasma bnp pediatrics

تعداد نتایج: 973985  

Journal: :JAMA 2009
Matthias Pfisterer Peter Buser Hans Rickli Marc Gutmann Paul Erne Peter Rickenbacher André Vuillomenet Urs Jeker Paul Dubach Hansjürg Beer Se-Il Yoon Thomas Suter Hans H Osterhues Michael M Schieber Patrick Hilti Ruth Schindler Hans-Peter Brunner-La Rocca

CONTEXT It is uncertain whether intensified heart failure therapy guided by N-terminal brain natriuretic peptide (BNP) is superior to symptom-guided therapy. OBJECTIVE To compare 18-month outcomes of N-terminal BNP-guided vs symptom-guided heart failure therapy. DESIGN, SETTING, AND PATIENTS Randomized controlled multicenter Trial of Intensified vs Standard Medical Therapy in Elderly Patien...

2013
Motoyuki Nakamura Yorihiko Koeda Fumitaka Tanaka Toshiyuki Onoda Kazuyoshi Itai Masaki Ohsawa Kozo Tanno Kiyomi Sakata Shinich Omama Yasuhiro Ishibashi Shinji Makita Mutsuko Ohta Kuniaki Ogasawara Takashi Komatsu Akira Okayama

OBJECTIVES Atrial fibrillation (AF) is a significant public health issue due to its high prevalence in the general population, and is associated with an increased risk of cardiovascular (CV) events including systemic thrombo-embolism, heart failure, and coronary artery disease. The relationship between plasma B-type natriuretic peptide (BNP) and CV risk in real world AF subjects remains unknown...

Journal: :Clinical science 2007
Leong L Ng Russell J O'Brien Paulene A Quinn Iain B Squire Joan E Davies

ORP150 (oxygen-regulated protein 150) is a chaperonin expressed in tissues undergoing hypoxic or endoplasmic reticulum stress. In the present study, we investigated plasma levels of ORP150 in patients with AMI (acute myocardial infarction) and its relationship with prognosis, together with a known risk marker N-BNP (N-terminal pro-B-type natriuretic peptide). Plasma from 396 consecutive patient...

2015
Hidetaka Hamasaki Hidekatsu Yanai Masafumi Kakei Mitsuhiko Noda Osamu Ezaki

OBJECTIVES In spite of accumulating evidences suggesting an inverse association between insulin resistance and plasma B-type natriuretic peptide (BNP) levels, the effect of daily physical activity on plasma BNP in individuals with glucose intolerance remains unknown. We investigated the association of physical activity level (PAL) with plasma BNP in patients with impaired fasting glucose, impai...

2017
Tamás Bárány Andrea Simon Gergő Szabó Rita Benkő Zsuzsanna Mezei Levente Molnár Dávid Becker Béla Merkely Endre Zima Eszter M Horváth

Background The present study aims to examine the oxidative stress-related activation of poly(ADP-ribose) polymerase (PARP), a cause of parthanatos in circulating mononuclear leukocytes of patients with chronic heart failure (CHF), that was rarely investigated in the human setting yet. Methods Patients with CHF (n = 20) and age- and body mass index-matched volunteers (n = 15) with a normal hea...

2013
Mona F. Schaalan Naglaa A. Gobba

Introduction: In practice, there is increasing recognition of the importance of BNP in the pathophysiology, diagnosis and prognosis of certain cardiac disorders, as ischemic cardiac dysfunction and heart failure. The association of BNP to obesity and characteristics of the metabolic syndrome in adults and aged patients is well established, but that in pediatrics needs thorough elucidation. Meth...

Journal: :Clinical chemistry and laboratory medicine 2011
Aldo Clerico Simona Vittorini Claudio Passino

Recent studies demonstrated that large amounts of the pro-hormone peptide of brain natriuretic peptide (proBNP) can be detected in plasma of healthy subjects and in particular of patients with heart failure. As a result, a great part of B-type natriuretic peptides measured in patients with cardio-vascular disease may be devoid of biological activity. These findings stimulated the set up of spec...

Journal: :European review for medical and pharmacological sciences 2017
L Zhang F Tang L-P Cai H-L Wang Z Wang

OBJECTIVE To investigate the correlation between the levels of urine calcium integrin binding protein-1 (CIB1) and serum precursor N-terminal brain natriuretic peptide (pro-BNP) and ischemic heart failure. PATIENTS AND METHODS 30 patients diagnosed as acute ischemic heart failure for the first time in our hospital from January to August 2016 were continuously selected as the observation group...

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