PURPOSE Standard chemoradiation therapy for stage III non-small cell lung cancer (NSCLCa) results in suboptimal outcomes with a high rate of local failure and poor overall survival. We hypothesize that dose escalation using stereotactic body radiotherapy (SBRT) boost could improve upon these results. We present here a study evaluating the dosimetric feasibility of such an approach. METHODS An...

BACKGROUND The aim of the present study was to introduce a new restricted tangential volumetric modulated arc therapy (tVMAT) technique for whole breast irradiation and compare its dosimetric properties to other currently used breast cancer radiotherapy techniques. METHOD Ten consecutive women with left-sided breast cancer were enrolled in this retrospective study. Four treatment plans were g...

introduction intensity-modulated radiotherapy (imrt) is becoming an increasingly routine treatment method. imrt can be delivered by use of conventional multileaf collimators (mlcs) and/or physical compensators. one of the most important factors in selecting an appropriate imrt technique is integral dose. integral dose is equal to the mean energy deposited in the total irradiated volume of the p...

PURPOSE Limited-tomotherapy and hybrid-IMRT treatment techniques were compared for reductions in ipsilateral and contralateral lung, heart, and contralateral breast radiation doses. METHODS AND MATERIALS Thirty consecutively treated left-sided early-stage breast cancer patients were scheduled for lTomo and hIMRT. For the hIMRT plan conventional tangential-field and four-field IMRT plans were ...

Background: This study evaluates the dose distribution of the wedged tangential beam three-dimensionally planned conformal radiotherapy (3D-CRT) compared to the previously used (5 years ago) two-dimensionally (2D-RT) planned radiotherapy of the chest wall for postmastectomy breast cancer patients in Clinical Oncology and Nuclear Medicine Department, Mansoura University. Patients and Methods: Th...

PurposePatients with locally advanced non-small cell lung cancer (LA-NSCLC) have a high prevalence of pre-existing coronary heart disease and face excess cardiac risk after thoracic radiation therapy. We sought to assess whether statin therapy is predictor overall survival (OS) therapy.Methods MaterialsWe performed retrospective analysis 748 patients LA-NSCLC treated therapy, using Kaplan-Meier...

BACKGROUND Interest in MR-only treatment planning for radiation therapy is growing rapidly with the emergence of integrated MRI/linear accelerator technology. The purpose of this study was to evaluate the feasibility of using synthetic CT images generated from conventional Dixon-based MRI scans for radiation treatment planning of lung cancer. METHODS Eleven patients who underwent whole-body P...

BACKGROUND To moving lung tumors, we applied a respiratory-gated strategy to carbon-ion pencil beam scanning with multiple phase-controlled rescanning (PCR). In this simulation study, we quantitatively evaluated dose distributions based on 4-dimensional CT (4DCT) treatment planning. METHODS Volumetric 4DCTs were acquired for 14 patients with lung tumors. Gross tumor volume, clinical target vo...

background: the potential hazards of exposure to radiation from radon have been of great concern worldwide, as it is associated with an increased risk of lung cancer. radon (222rn) and its progeny are the main sources of radioactivity in the environment. the half-life of 222rn (3.82 days) is long enough for it to diffuse into and build up in homes. 220rn or thoron from the 232th series, and 219...

Introduction: The purpose in this study is to analyze of DVH parameters as predictors of radiation pneumonitis and investigation on the relationship between dosimetric and clinical parameters based on PFTs as response in NTCP model and therefore achieve to lung dose- response relation in breast cancer patients. Prescribed dose to treatment volumes was 50 Gy in 2.0 Gy/fractions ...