Background: Although the incidence of Ventricular Septal Defects (VSD) has been reported in other reports on Congenital Heart Disease (CHD) in the region. None has considered VSD as a separate entity. Other previous studies on Congenital Heart Disease in the region had also been for a short period of time (at best two years) with fewer sample sizes hence the need for this study which aims to do...

In patients with congenital heart disease, the right heart may support the pulmonary or the systemic circulation. Several congenital heart diseases primarily affect the right heart including Tetralogy of Fallot, transposition of great arteries, septal defects leading to pulmonary vascular disease, Ebstein anomaly and arrhythmogenic right ventricular cardiomyopathy. In these patients, right vent...

Dextro-transposition of the great arteries (d-TGA) is the one most common cyanotic congenital heart disease in neonates. The discordant ventriculoarterial arrangement results in parallel circulation, it so is vital to understand the management. We report a rare interesting but critical case of 33-day-old boy who developed cyanosis and had transposition of great arteries combined with interrupte...

INTRODUCTION Congenital heart defects are common in infants and adults, affecting quality of life if not corrected. Unlike open surgery, percutaneous intervention allows correction with a high success rate and speedy recovery. In Mexico, there are not enough studies to describe their efficacy and safety. METHODS A cohort study was conducted in the Hospital "Manuel Avila Camacho", in Puebla, M...

A growing list of transcatheter interventions is now available for treating patients with congenital and acquired heart disease. Among these procedures are creation of interatrial defects by balloon and blade septostomy , , balloon dilation of stenotic vessels and valves, and closure of unwanted intracardiac and extracardiac defects and vessels. This chapter focuses on several interventions: ba...

BACKGROUND Cardiac development is a complex and multifactorial biological process. Heterozygous mutations in the transcription factor NKX2.5 are between the first evidence of a genetic cause for congenital heart defects in human beings. In this study, we evaluated the presence and frequency of mutations in the NKX2.5 gene on 159 unrelated patients with a diverse range of non-syndromic congenita...

Medical and surgical breakthroughs in the care of children born with heart defects have generated a growing population of adult survivors and spawned a new subspecialty of cardiology: adult congenital heart disease. The prevalence of adult congenital heart disease is escalating at a rampant rate, outpacing the relatively static prevalence of pediatric congenital heart disease, because adults no...

In the patients with congenital heart defects the various circulatory disorders are connected with their association in the pathogenesis of the primary manifestations being malformations of the cardiovascular system and secondary (chronic insufficiency of the cerebral circulation) mechanisms realized in the postnatal period. Evidently, in time diagnosis and appropriate tactics and management of...

The new concepts of cardiac anatomy and physiology, based on the observations made by Francisco Torrent-Guasp's discovery of the helical ventricular myocardial band, can be useful in the context of the surgical strategies currently used to manage patients with congenital heart defects. The potential impact of the Torrent-Guasp's Heart on congenital heart defects have been analyzed in the follow...

OBJECTIVE To analyse the spectrum of congenital heart malformations, the frequency of extracardiac malformations, and the proportion of chromosome aberrations among fetuses sent for necropsy. MATERIAL Necropsies were performed on 815 fetuses-448 induced abortions (55%), 220 spontaneous abortions (27%), and 147 stillbirths (18%)-during a seven year period (1991-97) in the department of patholo...