BACKGROUND Hepatitis B virus (HBV) is the commonest cause of primary hepatocellular (PHC) carcinoma worldwide. Co-infection with the HIV leads to more rapid progression of liver disease. OBJECTIVES We described prevalence of HBV and HIV among patients with PHC admitted to Mulago Hospital, Kampala, Uganda. METHODS We assessed all patients admitted to the gastrointestinal service of Mulago ho...

BACKGROUND There are few studies on pediatric HIV-HBV coinfection, so evidences about relationships between the two viruses are scarce. OBJECTIVES influence of HBV infection on virological and immunological response to antiretroviral therapy (ART) in antiretroviral-naïve horizontally HIV-HBV coinfected subjects during early childhood. MATERIAL AND METHODS observational study on 826 HIV+ sub...

BACKGROUND Hepatitis B virus (HBV) is a major global health problem especially in sub-Saharan Africa and in East Asia. Ten hepatitis B virus genotypes have been described that differ by geographic distribution, disease progression, and response to treatment. Escape mutations within the surface open reading frame (ORF) affect HBV antigenicity leading to failures in diagnosis, vaccine and hepatit...

context hepatitis b and hepatitis c (hbv and hcv) infections are both major causes of hepatocellular carcinoma (hcc). however, hcc caused by each of these two viruses has unique characteristics that should be studied independently to that of another one. while hbv- and hcv-related hccs share similar host and environmental risk factors such as male gender, age above 50 years old, family history ...

conclusions these findings suggest that nmr-based urinary metabonomics approach might be a useful tool for the clinical diagnosis of depression in hbv-infected patients and the six potential biomarkers could be helpful for developing an objective diagnostic method. limited by the number of recruited subjects, future studies are required to validate our conclusions. patients and methods in this ...

OBJECTIVES The association between hepatitis B virus (HBV) infection and cardiovascular disease remains uncertain. This study explored long-term hard endpoints (ie, myocardial infarction and ischaemic stroke) and all-cause mortality in diabetic patients with chronic HBV infection in Taiwan from 2000 to 2013. DESIGN This study was retrospective, longitudinal and propensity score-matched.Settin...

Introduction: Chronic hepatitis B (HBV) and C (HCV) virus infection is associated with the activation of hepatic stellate cells (HSCs) toward a myofibroblastic phenotype, resulting in excessive deposition of extracellular matrix, the development of liver fibrosis, and its progression toward cirrhosis. The gold standard for the detection and staging of liver fibrosis remains the liver biopsy, wh...

BACKGROUND Hepatitis B virus (HBV) is one of the most common chronic viral infections in the world. Iran has a low to intermediate HBV prevalence and approximately 1.5 million people are living with HBV infection. The impact of HBV in Iran is unknown and given the very low levels of alcohol consumption, this region provides an opportunity to examine the impact of isolated chronic HBV infection....

Regarding the article of Leonardi and La Rosa: "Are hepatitis B virus and celiac disease linked?", published in the 2010 issue of Hepatitis Monthly (1), we believe that there is no relationship between the hepatitis B virus (HBV) and celiac disease (CD). None of the study’s patients tested positive for immunoglobulin A anti-endomysium or immunoglobulin A anti-tissue transglutaminase antibodies,...