AIM To assess the relationship between weight change and glycated haemoglobin (HbA1c) change in dulaglutide-treated patients by analysing data from six head-to-head phase III AWARD clinical trials. METHODS At 26 weeks, the relationship between weight and HbA1c was analysed in each trial rather than by pooling data because of differences in design and background therapy. The effect of baseline...

BACKGROUND We investigated the effects of vildagliptin or alogliptin on blood glucose and hemoglobin A1c (HbA1c) in patients with type 2 diabetes inadequately controlled by sitagliptin. METHODS In a single-center open-label trial, 35 patients with inadequate glycemic control on sitagliptin therapy (50 mg once daily) were randomly switched to treatment with vildagliptin (50 mg twice daily) or ...

BACKGROUND Individual-level health outcomes are shaped by environmental risk conditions. Norms figure prominently in socio-behavioural theories yet spatial variations in health-related norms have rarely been investigated as environmental risk conditions. This study assessed: 1) the contributions of local descriptive norms for overweight/obesity and dietary behaviour to 10-year change in glycosy...

Diabetes mellitus (DM) is the most common endocrine disorder and one of highly progressive diseases which indicated by high blood sugar (hyperglycemia). The present study aims to effects treatment with zinc vitamin C on glycemic profile [fasting (FBS), glycated haemoglobin (HbA1C), insulin hormone level] in type 2 diabetic patients. included 56 patients [30 without foot ulcers (15 supplements, ...

Monitoring of the arterial condition promises an advantage in detection of any abnormalities occurred among diabetic patients. In this study, the characteristic of photoplethysmogram (PPG) has been investigated non-invasively to measure the status of arterial stiffness. A total of 101 Type 2 diabetic patients, aged 50 to 70 year were participated in this study. The patients divided into two gro...

INTRODUCTION Although insulin is one of the most effective interventions for the treatment of type 2 diabetes, its disadvantages incur substantial medical cost. This study was designed to evaluate the medical costs of Swedish type 2 diabetic patients initiating insulin on top of metformin and/or sulfonylurea (SU), and to evaluate if costs before and after insulin initiation differ for patients ...