This study was done to investigate the interaction effect of the mixture of each pair of traditional medicinal plants including: Sage (Salvia officinalis), Hawthorn (Crataegusoxyacantha), Walnut Leaf (Juglansregia L.), Red Cabbage (Brassica oleracea), and Yellow Sweet Clover (Melilotus officinalis) on the antioxidant activities and free radical scavenging by using DPPH (2, 2-diphenyl-1-picrylhy...

Crataegus oxyacantha (Aubepine, Hawthorn), was used by european herbalist in the first century A. D. It went out fashion as a medicine until the 19th century for heart disease. The leaves, flowers, and berries of hawthorn contain a variety of bioflavonoid-like complexes that appear to be primarily responsible for the cardiac actions of the plant. Bioflavonoids found in C. oxyacantha include oli...

Softening, a common phenomenon in many fruits, is a well coordinated and genetically determined process. However, the process of flesh softening during ripening has rarely been described in hawthorn. In this study, we found that 'Ruanrou Shanlihong 3 Hao' fruits became softer during ripening, whereas 'Qiu JinXing' fruits remained hard. At late developmental stages, the firmness of 'Ruanrou Shan...

Due to its high polyphenolic compound content, Chinese hawthorn, which belongs to the Rosaceae family, is a popular fruit consumed as food and medicine source in China. However, little genetic studies have been performed on hawthorn, partially because of the lack of genomic resources. To this end, we performed de novo transcriptomics analysis of hawthorn using the cost-effective Illumina paired...

Background and objectives: Hawthorn as an ethno-pharmaceutical plant has been consumed for 2,500 years. Flowers, leaves and fruits of hawthorn are rich in antioxidant and polyphenols and are popular in the treatment of congestive heart failure. Methods: In the present study, by using various media and plant hormones the regeneration and callogenesis capacity of...

The systematic assessment of the human immune system bears huge potential to guide rational development of novel immunotherapies and clinical decision making. Multiple assays to monitor the quantity, phenotype, and function of Ag-specific T cells are commonly used to unravel patients' immune signatures in various disease settings and during therapeutic interventions. When compared with tests me...

Although the TCR repertoire is highly diverse, a small fraction of TCR chains, referred to as public, preferentially form and are shared by most individuals. Prior studies indicated that public TCRβ may be preferentially deployed in autoimmunity. We hypothesized that if these TCRβ modulate the likelihood of a TCRαβ heterodimer productively engaging autoantigen, because they are widely present i...