Rats artificially selected as low capacity runners (LCR) exhibit features of the metabolic syndrome, and blunted exercise training-induced cardiac hypertrophy compared with high capacity runners (HCR). We tested the hypothesis that the divergent cardiac phenotypes may be due to diminished activation of signaling proteins in LCR vs HCR rats. LCR (n=18) and HCR (n=18) rats were randomly assigned ...

Comparative genomic analyses of Leishmania species have revealed relatively minor heterogeneity amongst recognised housekeeping genes and yet the species cause distinct infections and pathogenesis in their mammalian hosts. To gain greater information on the biochemical variation between species, and insights into possible metabolic mechanisms underpinning visceral and cutaneous leishmaniasis, w...

Literature on microgreens, an emerging new functional food crop, remains limited. Further study microgreens as a promising dietary component for potential use in diet-based disease prevention is, therefore, essential. Given that the anti-inflammatory and anti-oxidant properties of mature licorice root material are well-documented, objective present, preliminary was to present (Glycyrrhiza g...

Aluminium toxicity in acidic soils adversely affects wheat growth. Foliar-applied magnesium (Mg) contributes to mitigating soil acidity stress wheat, but the mechanisms are unknown. This study explored mechanism of foliar-Mg mediated enhancement growth soil. Two contrasting near-isogenic (Triticum aestivum L.) genotypes differing Al resistance (Al-sensitive ES8 and Al-resistant ET8) were grown ...

In recent contributions to the theory of public pension systems it was argued that a Paretoimproving transition from an established unfunded pension system to a funded one is possible. This result is derived in an overlapping-generations model with identical individuals. In the present study an extended model, with differing individuals, of an intragenerationally fair unfunded pension scheme is...

We define epistemic order as the way in which the exchange and development of knowledge takes place in the classroom, breaking this down into a system of three components: epistemic initiative relating to who sets the agenda in classroom dialogue, and how; epistemic appraisal relating to who judges contributions to classroom dialogue, and how; and epistemic framing relating to the terms in whic...

There are two possible contributions to the heterogeneity of mucus glycoproteins as observed in the analytical ultracentrifuge: firstly, from associative phenomena, and, secondly, from a polydisperse distribution of non-interacting species of different molecular masses. It is shown from the non-superposability of plots of point-weightaverage relative molecular masses against concentration for d...

We give a systematic discussion of the contributions to the cosmological energy density in axions from vacuum realignment, string decay and wall decay. We call these the cold axion populations because their kinetic energy per particle is at all times much less than the ambient temperature. In case there is no inflation after the Peccei-Quinn phase transition, the value of the axion mass for whi...

Analysis of the kinetics of hybridization in liquid of labeled herpes simplex virus-1 DNA and excess viral RNA revealed the following: (i) Cells infected by herpes simplex virus-1 for 2 hr (before DNA synthesis) contain two classes of RNA molecules differing 140-fold in molar concentrations. The abundant and scarce RNAs are transcribed from 14 and 30% of the DNA, respectively. RNA extracted at ...

The nicotinic acetylcholine receptor (AChR) can be either hetero-pentameric, composed of alpha and non-alpha subunits, or homo-pentameric, composed of alpha7 subunits. To explore the subunit-selective contributions of transmembrane domains to channel gating we analyzed single-channel activity of chimeric muscle AChRs. We exchanged M3 between alpha1 and epsilon or alpha7 subunits. The replacemen...