lesions occurred in up to a third of patients who initially responded to alitretinoin after 24 weeks of follow-up. A recent study reported that a second course of treatment with alitretinoin at a dosage of 30mg/d in patients who relapsed achieved clearance in up to 80% of cases, with good tolerance; this would indicate that this medication could be used for long-term management of chronic hand ...

due to increasing worldwide water pollution, fish might be a source of excessive zinc, mercury, arsenic or  manganese  intake. the  aim  of  this  study  was  to  evaluate if  fish atopy/sensitization and fish consumption behavior are associated with eczema severity and blood levels of the 4 heavy metals. one-hundred and nineteen patients with eczema and 43 patients with miscellaneous non-eczem...

BACKGROUND Alitretinoin (9-cis-retinoic acid) is an endogenous derivative of vitamin A and functions as an agonist of both families of nuclear receptors (retinoic acid receptor-α, -β, -γ; retinoid X receptor-α, -β, -γ). It has been investigated in the treatment of chronic hand eczema in many studies in recent years and the results have been promising. OBJECTIVES To evaluate the efficacy and s...

Skin lesions, such as atopic dermatitis and eczema, are often colonized with high densities of microorganisms, especially Staphylococcus aureus (1–3). Severity and persistence of both atopic and hand eczema has been associated with S. aureus colonization (2, 4). Besides colonizing eczema S. aureus is also one of the most frequently found contaminants in cosmetic products (5–7), and cosmetics co...

Contact dermatitis is not a homogenous entity, but rather a number of subtypes contributing to different clinical presentations. For better understanding, instructional sheets provide information that assists in patient care. Informational sheets on contact dermatitis, patch testing, hand dermatitis, stasis dermatitis, and poison ivy are reviewed for open forum. Although often considered archai...