نتایج جستجو برای: hadscs
تعداد نتایج: 147 فیلتر نتایج به سال:
BACKGROUND Considering promising results in animal models and patients, therapeutic use of MSCs for immune disease is likely to undergo continued evaluation. Low-lever laser (LLL) has been widely applied to retard the inflammatory reaction. LLL treatment can potentially be applied in anti-inflammatory therapy followed by stem cell therapy. AIM OF THE STUDY The purpose of this study was to inv...
Human adipose-derived stem cells (hADSC) are capable of differentiating into an osteogenic lineage. It is believed that microRNAs (miRNAs) play important roles in regulating this osteogenic differentiation of human adipose-derived cells, although its molecular mechanism remains unclear. We investigated the miRNA expression profile during osteogenic differentiation of hADSCs, and assessed the ro...
The use of mesenchymal stem cells (MSCs) for cell therapy and regenerative medicine has received widespread attention over the past few years, but their application can be complicated by factors such as reduction in proliferation potential, the senescent tendency of the MSCs upon expansion and their age-dependent decline in number and function. It was shown that all the mentioned features were ...
MicroRNAs (miRNAs or miRs) play an important regulatory role during adipogenesis, and have been studied extensively in this regard. Specifically, the switch between the differentiation of mesenchymal stem cells (MSCs) towards adipogenic vs. osteogenic lineages is regulated by miR-204 which controls the expression of Runx2. However, the association between miR-204-5p and the Wnt/β-catenin signal...
Objective(s): Neurotrophic factors secreting cells (NTS-SCs) may be a superior cell source for cell-based therapy in neurodegenerative diseases. NTS-SCs are able to secrete some neurotrophic Such as nerve growth factor and glia-derived neurotrophic factor. Our primary aim was to assess transplantation of neurotrophic factor secreting cells derived from human adipose-derived stem cells (hADSCs) ...
به عنوان مدل 3 بعدی، روش میکروکپسوله کردن اثر چشم گیری در مهندسی بافت و سلول درمانی، داشته است. درمان های جایگزینی سلول، با استفاده از منابع تجدید پذیر سلول های بنیادی، پتانسیل فوق العاده ای برای درمان گستره وسیعی از بیماری ها دارد. میکروکپسول های آلژیناتی قابلیت ایجاد سد ایمنی برای سلول های کپسوله شده را دارند که از سلول های انتقال یافته در برابر سیستم ایمنی بدن میزبان حفاظت می کند. با وجود ا...
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