helicobacter pylori infection is a common gastrointestinal infection that can cause pathological effects, increase oxidative stress and induce an inflammatory response in gastric mucosa. inflammatory aspects may prompt the production of radical oxygen substance (ros) which may damage cells and release 8-hydroxydyoxyguanosine (8-ohdg) to serum. in this study, we evaluate the prevalence of h. pyl...

OBJECTIVES Helicobacter pylori (H. pylori) infection plays an important role in the carcinogenesis and development of gastric cancer. Eradication of H. pylori can effectively reduce the risk of gastric cancer, but the underlying mechanisms are not fully understood. This study aimed to investigate the effect of eradication of H. pylori on the expression levels of FHIT, IL-8 and P73 in the gastri...

background helicobacter pylori (h. pylori) infection usually occurs during childhood, especially in developing countries. the aim of this study was to evaluate the prevalence of h. pylori infection among children in primary schools of rasht, a northern iranian city. methods this cross-sectional study was conducted among 961 primary school students in rasht. samples were randomly selected and st...

INTRODUCTION. Helicobacter pylori infection can be diagnosed by biopsy-based or noninvasive methods. Our aim was to identify H pylori-positive patients on hemodialysis by the noninvasive method of H pylori stool antigen (HPSA) and investigate its diagnostic accuracy for assessment of the eradication of infection after treatment in comparison with urea breath test (UBT). MATERIALS AND METHODS. S...

background: gastric cancer (gc) is the most common gastrointestinal cancer in iran. helicobacter pylori (h. pylori) accounts as one of the main risk factors for gastric non-cardia cancer (gncc). it is suggested that high serum selenium level may have a protective role in gncc. in this cross-sectional study, we determined the serum se level and the status of h. pylori infection in two population...

Idiopathic thrombocytopenic purpura (ITP) is an autoimmune hematological disorder characterized by auto antibody-mediated platelet destruction. Although the main cause of ITP remains unclear, but its relationship with some infection was demonstrated. In recent years, many studies have demonstrated improvement of platelet counts in ITP patients after treating Helicobacter pylori infection. The a...

The aim of this study was to investigate the effect and mechanism of Helicobacter pylori infection in the invasion and metastasis of gastric cancer. Specimens from 80 patients with gastric cancer (of which 20 patients had metastatic gastric cancer) and 40 patients with chronic gastritis were included in this study. H. pylori infection was determined by ELISA and the expression of matrix metallo...

AIM To explore the association between Helicobacter pylori (H. pylori) infection and obesity/weight gain in a Chinese population. METHODS Our primary outcome was the change in body mass index (BMI). The generalized linear models were used to explore the association between H. pylori infection and the change of BMI, and the logistic regression models were used to explore the association betwee...

aim: the objective of this study was to evaluate the time trend of helicobacter pylori ( h. pylori ) prevalence and presence of intestinal metaplasia over the period of 7 years in gastritis iranian patients. background: h. pylori are the major causal factor in chronic gastritis. its acquisition leads to a chronic, usually lifelong, inflammation of the gastric mucosa, which may gradually progres...